INTRACELLULAR PflTASSIUM— TAYLOR 31 



shortly. I'urtluT cxaliKition of this ])lK'n(iiiicii(>n ami the intcrpretatiuu ui its signili- 

 cancc must await studies with radioactive tracers. 



Dr. Calkins: I have read Dr. 'I'aylor's pajjer to you and would like to add a final 

 comment of my own. It seems aj^parent that des])ite the experience with the isolated 

 rat and hamster diaphragm, there is reason to douI)t that loss of intracellular potas- 

 sium per sc has any direct relationshij) to the cause of death from hvpothermia. 



refer1':ncI':s 



1. Krogh, A. : Croonian lecture : Tlie active and passive exchanges of inorganic ions through the 



surfaces of living cells and through living membranes generally, Proc. Roy. Soc, London, 

 Series B 133: 140-200, 1946. 



2. Clarke, Hans T., Editor : Ion transport across membranes, Academic Press, Inc., New York, 



N.Y., 1954. 



3. Wesson, L. G., Jr., Cohn, W. E., and Brues, A. M. : The effect of temperature on potassium 



equilibria in chick embryo muscle, J. Gen. Physiol. 32: 511-523, 1949. 



4. Turner, C, Eggleston, L. V., and Krebs, H. A. : The role of glutamic acid in the transport 



of K* in brain and retina, Biochem. J. 47: 139-149, 1950. 



5. Raker, J. W., Taylor, I. M., Weller, J. M., and Hastings, A. B. : Rate of K* exchange of 



the human erythrocyte, J. Gen. Physiol. 33: 691-702, 1950. 



6. Calkins, E., Taylor, I. M., and Hastings, A. B. : Potassium exchange in the isolated rat 



diaphragm: Effect of anoxia and cold. Am. J. Physiol. 177: 211-218, 1954. 



7. Adolph, E. F. : Responses to hypothermia in several species of infant mammals, Am. J. 



Physiol. 166: 75-91, 1955. 



