286 PHYSIOLOGY OF INDUCED HYPOTHERMIA 



must be rememljered that in the hypothermic animal the connecting hnk between 

 these systems, the circulation, has also been markedly altered. Therefore, the 

 imbalance of various metabolic chains in one system may not be transmitted 

 properly to another system to produce either a favorable or deleterious secondary 

 response. This emphasizes the intimate interrelationships of the various portions of 

 the central nervous system and the products of the endocrine glands upon the 

 response of the total organism. Studies striving to demonstrate this interrelation 

 should prove to be most fruitful in clarifying the physiological processes inherent 

 in the hypothermic state. 



There seems to be one point of agreement among all investigators, namely that 

 there is a decrease in the oxygen consumption in all systems of the organism in 

 hypothermia and that this decrease may induce other effects which at the present 

 time have not been completely evaluated. 



