ISCHEMIA AND C.N.S.— PONTIUS and DE BAKEY 



269 



Cose 



J S 



53 dW 



JH 



eedc 



WK 

 54dW 



Etiology 



Arterio- 

 sclerotic 



Syphilis 



Dissection 



Dote of 

 Operation 



8-30-55 



8-31-55 



9-15-55 



Period of 

 Occlusion 



38 mm 



lOOnnin 



53 mm 



Location 

 end Technic 



Result 



Recovered 



Died- 1 week 



later 

 Segment of 



infarcted 

 bowel 



Recovered 



Fig. 8. — Chart of clinical cases zvitli hypothermia. 



3. Four of five patients with aneurysms of the thoracic aorta in whom the aorta 

 was occluded for a period of about one hour developed evidence of spinal cord 

 damage following resection. None of 14 similar cases in which hypothermia was 

 employed developed any evidence of spinal cord damage. 



4. On the basis of these experimental and clinical observations it would appear 

 that hypothermia increases the tolerance of the tissues of the central nervous sys- 

 tem to periods of temporary ischemia. 



REFERENCES 



1. Beattie, E. J., Jr., Adovasio, D., Keshishian, J. M., and Blades, B. : Refrigeration in experi- 



mental surgery of the aorta, Surg., Gynec. & Obst. 96: 711-713 (June) 1953. 



2. Bigelow, W. G., Callaghan, J. C, and Hopps, J. A. : General hypothermia for experimental 



intracardiac surgery, Ann. Surg. 132: 531, 1950. 



3. Bigelow, W. G., Lindsay, W. K., Harrison, R. C., Gordon, R. A., and Greenwood, W. F. : 



Oxygen transport and utilization in dogs at low body temperatures. Am. J. Physiol. 160: 

 US, 1950. 



4. Carrel, A. : Report on the exix?rimental surgery of the thoracic aorta and heart, Ann. Surg. 



52: S3. 1010. 



5. De Bakey, M. E., and Cooley, D. A.: Excisional therapy of aortic aneurysms. Am. Surg. 19: 



603 (July) 1953. 



6. Gross, R. E. : Coarctation of the aorta, Circulation 7; 757 (May) 1953. 



