HEMORRHAGIC SHOCK— OVERTON and De BAKEY 389 



tion of all the listed factors, either separately or in the various combinations. The 

 drug in large dosage conil)ined with hypothermia proved the most effective. A 

 protective mechanism was also suggested by the increased tolerance to hypotension 

 in the treated animals. This improvement was noted both in terms of hypotension 

 time and in the number of animals which were still compensated after 8 hours of 

 shock and their experiment arbitrarily terminated. Combination of the drug, in 

 either small or large dosage, with hypothermia proved to be most effective therajn-. 



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