F. J. W. ROUGHTON, J. W. LEGGE and P. NICOLSON 



80 



60 



<X 40 



20 



Figure 3. Calculated rate of CO uptake 

 by layer of haemoglobin solution of same 

 thickness and concentration as in red 

 blood corpuscle, compared with rate of 



CO + Hb > CO Hb in homogeneous 



solution (full lines). Dotted lines rep- 

 resent maximum and minimum solutions 

 previously obtained by Roughton 6 . 



002 004 006 008 

 Time in Seconds 



O-JO 



Figure 4. Calculated rate of0 2 uptake by 

 layer of haemoglobin solution of same 

 thickness and concentration as in red blood 

 corpuscle, compared with rate ofO t -\- Hb 



> 2 Hb in homogeneous solution (full 



lines). Dotted lines represent maximum 



and minimum solutions previously obtained 



by Roughton 6 . 



001 

 Time m Seconds 



002 



002 003 



Tune in Seconds 



004 



OOS 



Figure 5. Observed rates of 

 uptake of CO by haemoglobin 

 solution and corpuscle suspen- 

 sion of blood of pregnant ewe 

 (full lines). Dotted lines rep- 

 resent calculated rates of up- 

 take by layer of haemoglobin 

 solution (of same thickness and 

 concentration as in red blood 

 corpuscle) enclosed by mem- 

 branes with 1/x values of 2-0 

 and 3-0 respectively. 



78 



