II 



REVERSIBLE REACTIONS WITH OXYGEN 

 AND CARBON MONOXIDE 



PAGE 



1 Aspects of the Oxygenation and Oxidation Functions 35 



Professor David L. Drabkin, A.B., M.D., Professor and Chair- 

 man of the Department of Physiological Chemistry, The Graduate 

 School of Medicine, University of Pennsylvania 



2 The Bond between Haem and Globin 53 



Professor Felix Haurowitz, M.D., Sc.D., Istanbul University, now 

 Professor of Chemistry, Indiana University 



3 The Electronic Stricture of the Haem Group in Haemoglobin 57 



Professor Linus Pauling, Ph.D., Sc.D., Hon. Mem. R.I., For. 

 Mem. R.S., California Institute of Technology 



4 The Kinetics of Haemoglobin in Solution and in the Red 



Blood Corpuscle 67 



Professor F. J. W. Roughton, F.R.S., Department of Colloid 

 Science, Cambridge University ; J. W. Legge, M.Sc, Department 

 of Biochemistry, University of Melbourne, and P. Nicolson, 

 Ph.D., Cambridge University 



5 The Intermediate Compound Hypothesis in relation to the 



Equilibria and Kinetics of the Reactions of Haemoglobin 

 with Oxygen and Carbon Monoxide 83 



Professor F. J. W. Roughton, F.R.S., Department of Colloid 



Science, Cambridge University 



6 Some Physico-Chemical Evidence regarding the Structure of 



Haemoglobin 95 



Professor Jeffries Wyman, Jr., Biological Laboratories, Harvard 

 University 



33 



H— 3 



