



2&C J^L 



&u* 



Fig. 61 



Paraffin section, normal mouse skin, stained eosin-toluidine blue ( 140). The mast cells (dark 



spots) are seen at the level of the hair follicles and again, more deeply, close to the muscle, 



The epidermis is but 2 to 3 cells thick. 





.*-. 



5o< 



•3Nr# _ - - __ - .„ - 



l» _ 





.•* 



U1 



, 



Fig. 62 



Mouse Skin one month after a single massive painting with a carcinogenic hydrocarbon in a 



non-irritant solvent. The epidermis is now many cells thick, the sebaceous glands have gone 



and the hair follicles are clubbed and distorted. Note the numerous small mast cells which are 



appearing under the hyperplastic epidermis. Eosin-toluidine blue (x 160). 



