MIYA, MARCUS AND PHELPS 



Temperature of Mortality LD^q (95% 



Experiment Dose Organism Ratio Confidence Limits) 



20 c 



2° C 



21° C 



210 C 



Table I. LDg^ 

 2° C(P) and 21° C(NP) following intraperitoneal injection. 



three temperature curves appear to parallel each other. 



In Figure 10 are presented the results of temperature measure- 

 ments obtained on singly- caged mice maintained at 2° C. Again the 

 three temperature curves parallel each other, and the temperature 

 difference is of the following descending order: rectal, upper res- 

 piratory cavity, skin. The rectal temperatures are not significantly 

 greater than the upper respiratory cavity temperatures, but they do 

 show consistently higher values. Similar to the results obtained with 

 the grouped mice, the skin temperatures of the singly- caged mice 

 are considerably lower than the rectal and upper respiratory cavity 

 temperatures. It is of interest to note that an initial rise in temper- 

 ature occurs within one hour after exposure to the low ambient en- 

 vironment, and is then followed by a sharp drop in temperatures 

 which reaches a maximal fall by four hours post- exposure. From 

 this point the temperatures gradually rise to reach stability by 24 

 hours post- exposure. The time of stabilization appears to be the 

 same as that required for the grouped mice. 



166 



