MIYA, MARCUS AND PHELPS 



WALKER: I was wondering about the difference between your 

 mice and mine in readjusting their temperatures. That em- 

 phasizes the difference in mice, I believe. 



MARCUS: Well, actually we are both using albino Mus mus cuius . 



WALKER: Yes, but we are using a colony that we have that is 

 originally derived from Webster-Swiss mice. 



PREVITE: Are your housing conditions the same? 



WALKER: Ours were in wire cages with metal bottoms and 

 no bedding, but with five or six animals per cage. 



PREVITE: No bedding? I think you mentioned using sawdust 

 and something else, I had a question about rectal temperatures in 

 acclimatized mice. It rather intrigues me in that you report the 

 rectal temperatures ar 1° C to 2° C higher 40 to 45 days after 

 acclimatization. 



MARCUS: No, not 45 days. This occurred within 24 hours. Dr. 

 Miya showed a chart of the effect of measuring their tempera- 

 tures as a function of the distance in the colon from a depth of 

 2 cm. He had points of 2.0, 1.5, 1.0, and .5 cm in the animal. 



PREVITE: Does this persist, this elevated temperature, or is 

 it something that is transient? 



MARCUS: No, it persists and remains fairly steady. 



PREVITE: This is what I mean. Once this temperature goes 

 up, it stays up. 



MARCUS: That is true, 1° C to 2° C higher than the normal, 

 and this is with the probe uniformly inserted all the time. 



PREVITE: Do you have any possible explanation? Why should 

 the temperature go up? I have no idea why it would go up. 



MIYA: As you probably know, there is a report, which I be- 



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