TUNEVALL AND LINDNER 



Normothermic mice (15) 



50 60 



hours 



120 000 pneumococci i.p 



start of hypothermia 



Hypothermic mice (16) 



Start of rewarming 



20 000 pneumococci i p 



Figure 8. l^esults of post mortem blood cultures in normothermic mice and hypo- 

 thermic ones given 2aOOO pneumococci Type III intraperitoneally. + =1-50 colonies, 

 ++ = 51-500, +++ = more than 500. 



for 46 hours or more, seven animals had coliform bacteria in 

 blood and/or peritoneum. 



The first experiment was only semi-quantitative and indicated 

 just the final result of the infection, because post mortem cultures 

 only were made. In the following study the events were followed 

 more closely. 



In the experiment reported in Figure 9, 15 mice were made 

 hypothermic while another 15 received the pretreatment only. All 

 mice were inoculated (i.p.) with 200,000 Type II pneumococci eight 



256 



