PERITONITIS AND BACTEREMIA IN MICE 



log number of bacteria 

 per ml blood 



10 20 30 40 50 60 70 80 90 100 110 120 



min after injection 



Figure 6. Results of blood cultures in mice at different times after the intravenous 

 injection of E. coli suspensions. The points denote logarithmic means. Numbers of 

 mice in each group and number of bacteria injected are given in the figure. 



In normal animals the initial elimination was rapid in this series 

 also, leading to complete disappearance of bacteria from the blood. 

 In hypothermic animals the 4 minute counts gave higher numbers 

 which increased with the length of the previous period of hypo- 

 thermia. Further, the eliminationprocess was interrupted after 2 or 



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