MIRAGLIA AND BERRY 



Treatment Per cent of tissues positive 



for staphylococci* 



Table V, Staphylococci recovered from tissues of mice after various treatmenis. 

 All Isolates were coagxilase- negative. Number of mice tested shown In parentheses. 

 ^Tissues tested: liver, kidney, spleen, lung and heart. 



strains. Table V summarizes the results. The intestine when 

 colonized with the coagulase-positive Giorgio strain could not 

 be the origin, therefore, of the secondary invader. But even 

 more revealing is the fact that staphylococci were still iso- 

 lated from the tissues of cold exposed mice with the anticipated 

 frequency in individuals whose feces contained no culturable 

 staphylococci. 



Reestablishment of coagulase- negative staphylococci in the gut 

 of mice rendered free of staphylococci by acid treatment did not 

 alter the frequency of tissue invasion by coagulase- negative organ- 

 isms. This too is evidence against the possibility that the invaders 

 are intestinal in origin. 



In tissues of acid- treated cold exposed mice, a few cases were 

 recorded in which both coagulase-positive and coagulase- negative 

 strains were found in the same individual but only one type was pre- 

 sent in any particular organ. In cases where coagulase-positive 



284 



