TUNEVALL AND LINDNER 



A Not treated 



BEFORE 

 HYPOTHERMIA 



•/, W9mice 



AFTER 

 24 HOURS 



80 mice 



AFTER 

 A8 HOURS 



78 mice 



AFTER 

 66 HOURS 



30 mice 



AFTER 

 78 HOURS 



29mice 



B Treated 



](-f)and -f C = Cdiforms 

 j ♦+ E: Enterococci 



I ♦ •♦• + Pz Proteus 



Figure I. Results of fecal cultures after different periods of hypothermia. 



The Development of Bacteremia in Hypothermic Mice 



In four consecutive experiments, in which 34 mice not anti- 

 bacterially treated were used, repeated blood cultures were made 

 after various periods of hypothermia. The results are reported 

 separately for the four experiments in Figure 2. In 8 mice bac- 

 teremia occurred after only 24 to 29 hours of hypothermia. After 

 48 to 54 hours, the number of bacteremic animals had increased 

 to 14, After 78 hours, only three mice remained alive and free 

 from bacteria in their blood, and of these, two mice soon suc- 

 cumbed in a bacteremic state. 



The same events are described for all four experiments to- 

 gether in Figure 3, this time with different bacterial species re- 



242 



