90 The Lymphocyte and Lymphocytic Tissue 



primary response to bovine serum albumin do not eliminate antigen until 

 the tenth or twelfth day after stimulation. None of the x-rayed recipients 

 which received only antigen demonstrated an immune pattern of antigen 

 elimination. No antibody was detected in the sera of those rabbits which 



Fig. 7-7. Recipient site 8 days after transfer of living lymph node cells. Hematoxylin- 

 eosin stain, (x 1800) 



received only live cells without antigen; rabbits which received killed cells 

 and antigen did not have an immune pattern of antigen elimination. 



The maximum concentration of circulating precipitating antibody which 

 was present in the sera of recipients from three to four days after the elimina- 

 tion of antigen averaged about 20 ^g. of antibody nitrogen in each milliliter 

 of serum. At this time the weight of the total antibody in the recipient was 

 equivalent to approximately one fourth of the wet weight of the transferred 

 lymphocytes. When that value is converted to molecules of antibody per 



