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Fig. 3-10 through 3-18. Photographed From supravital films with the phase contrast 

 microscope (dark medium contrast). (X 2000; reduced 25 per cent) 



Figs. 3-10 and 3-11. Lymphocytes from chronic lymphatic leukemia. Note hyper- 

 chromatic nuclei, small nucleoli, and "nucleolar associated chromatin." Cytoplasm is 

 scanty and contains numerous small spherical mitochrondria and a few slightly larger 

 neutral red staining granules. A lymphoblast is present in Fig. 3-11, possessing a prom- 

 inent cytocentrum surrounded by granules, and mitochondria are scattered throughout 

 the ( ytoplasm. 



Figs. 3-12 through 3-16. Variations in the morphologic structure of the lymphocytes 

 ol leukolymphosarcoma. Granules and spherical mitochondria localize in the hof. Cyto- 

 plasm is basophilic and opaque. The chromatin pattern is variable, appearing either 

 vesicular (Figs. 3-13, 3-15. and 3-16) or hyperc hromatic (Figs. 3-12 and 3-14). A large 

 immature lymphosarcoma cell is illustrated in Fig. 3-15. 



Figs. 3-17 and 3-18. Lymphoblasts from acute lymphoblastic leukemia. Note vesicular 

 nuclei, large prominent nucleoli, thin nuclear membrane, and a large number of cyto- 

 plasmic organelles, primarily mitochondria. 



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