126 



TJic Lymphocyte and Lymphocytic Tissue 



Fig. 10-1. Morphologically normal lymphocytes. 

 Note: Figs. 10-1 through 10-6 are prints from a l(i 

 mm. cinemicrographic film of rabbit lymphocytes 

 irradiated with 1000 r. The headings give a code letter 

 for the individual cell and the time of incubation at 

 37° C. after irradiation in hours and minutes, (x 1750) 



D i: 27 E 2:31 F 3: 3 



\ * 1 



■ m 



Fig. 10-2. Early intranuclear vacuoles in lymph- 

 ocytes irradiated with 1000 r. (See Note. Fig. 10-1). 



C 0:44 E 2:38 



1 



> 



F 3 : I 4 



mm 



Fig. 10-3. Early changes in shape of irradiated 

 lymphocytes and their nuclei. (See Note. Fig. 

 10-1.) 



semicircle, and finally a small pyknotic and sometimes fragmented nucleus 

 (Fig. 10-6). The nonirradiated lymphocyte also dies by the process of intra- 

 nuclear vacuolization (Fig. 10-7). The only difference is that the non- 

 irradiated cell develops intranuclear vacuoles later than the irradiated cell. 

 It seems that irradiation with 1000 r or less does not produce any new 

 reactions in the Lymphocyte but only accelerates normal degenerative 

 changes. 



