Histopathology in Prognosis & Therapy of Lymphocytic Lymphomas 223 



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Fig. 17-9. Case 9, chronic lymphatic leukemia. (A) Bone marrow, severe 

 fat atrophy secondary to over treatment, (x 80) (B) Higher power of A. 

 Residual island of small lymphocytes (5) and a few myelocytes (G) and 

 erythroblasts (£). (x 650) 



benign course were similar to Cases 5 and 6, i.e., they needed therapy least. 

 In fact, it appears that one of the effects of radiation or radiomimetic therapy 

 has been to reduce the red cell survival, 22 a most undesirable sequel. As the 

 extent of marrow replacement progressed to the degree seen in Case 7, 

 therapy, with the possible exception of steroids, was usually of no avail, 



