WALKER 



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20. Walker, D. L., and W.D. Boring. 1958. Factors influencing host- 



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DISCUSSION 



CAMPBELL: It seems to me that the enzyme system shown 

 in Figure 1 is an unusually sensitive system as far as kinetics 

 go. If you were to plot the effect of temperature on your enzyme 

 reaction, what would you find? 



METCALF: We have done this repeatedly; I would say possibly 

 30 or 40 times. 



CAMPBELL: I am not questioning the results. It's just so 

 unusual. Earlier this afternoon somebody talked about the sen- 

 sitivity of viruses to temperature as far as susceptibility goes, 

 so this is a rather unusual reaction. Didn't you notice that the 

 effect of temperature between 37*-* C and 20° C is really a tre- 

 mendous difference in the activity of your enzyme? 



METCALF: In other words, Dr. Campbell, you think that this 

 is more than would seem to be indicated by experience with 

 other systems ? 



CAMPBELL: Well, it's a little different, I would think. It 

 would be really interesting to do a kinetic study on it. 



338 



