ANDREWES 



had only slightly falling antibody to his original strain and this 

 has been quite unaffected by his attacks of these other colds. 



WALKER: And his antibody came up in a matter of a couple 

 of weeks? 



ANDREWES: I can't recall, but fairly soon. 



WALKER: As I recall, the reports of Jackson and Bowling 

 show that this was much slower in their experience. 



ANDREWES: I don't remember their doing it with antibodies. 



WALKER: It seems to me they got a peak only after six months 

 or a very prolonged period of time, which is strange, 



SCHMIDT: I wonder if you might have a comment on the work 

 that I think has been done by Kruger and others concerning 

 the concentration of the negative or positive charged ions in 

 the atmosphere and its effect on the mucosal lining. 



ANDREWES: 1 am afraid I don't know about that. 



TUNEVALL: There is one thing that relates to that season 

 of the year, and that is when our children return from their 

 holiday to school. Couldn't the incidence of colds perhaps be 

 correlated to these instances when the children get together? 



ANDREWES: Well, there is no doubt that children are very 

 much more effective spreaders of infection than adults. We car- 

 ried out some epidemiological studies in a rural valley near 

 Salisbury, and it was found that colds in adults in families in 

 which there were school-age children were two and a half times 

 as common as in families when there were no school- age children. 

 There is no doubt that the little darlings spread the virus very 

 efficiently. 



1 Krueger et al. 1959. Proc. Soc. Exp. Biol. Med, 102: 355-357. 



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