112 



GENETIC STOCKS AND BREEDING METHODS 



As in the case of the rats, it is suggested that (1) the rules recommended by the 

 Committee on Standardized Genetic Nomenclature for Inbred Strains of Mice be 

 adopted for inbred guinea pig strains, and that (2) the strain symbols herein used 

 be immediately adopted. Also, possibly the jurisdiction of the Committee will be 



Tabic 31 

 Established strains of guinea piGsf 



Name or 

 Symbol 



Synonym(s) 



Remarks 



13 



C/A inbr: F 19 . origin: O. Miihlbock, 1948. charac: No information 



submitted, maintained by: A. 



Family 2, inbr: F 26 +• origin: U.S. Department of Agriculture, 1906, to S. 



Strain 2, Wright, 1915, at F u ; b x s matings for 33 generations (1933), then 



STR. 2 within strain random breeding until 1940; to Heston, 1940, at which 



time b x s mating system restored; to N, 1950, at F 12 ; all subsequent 

 sublines from the N colony, charac: fairly resistant to tuberculosis, 

 N subline has median incidence of deciminated calcification occurring 

 in greater curvature of stomach, colon, kidney, striated muscle of the 

 abdominal wall, lung, and aorta of old animals (34 mo.). Medium 

 reproduction, active sexual behavior, small body size, isohistogenic, 

 tricolor (black, red, white), maintained by: Bk, Fn, Ju, N, Ne, Sm, 

 Ss, Wal, Yo. 



Family 13, inbr: F 26 +. origin: U.S. Department of Agriculture, 1906, to S. 



Strain 13, Wright, 1915, at F 13 ; b x s matings for 33 generations (1933), then 



STR 13 within strain random breeding until 1940; to Heston, 1940, at which 



time b x s mating system restored; to N, 1950, at F 12 ; all subsequent 

 sublines from the N colony, charac: less resistant to tuberculosis 

 than Strain 2, medium reproduction, less active sexual behavior than 

 Strain 2, larger body size than Strain 2, isohistogenic, tricolor (black, 

 red, white), maintained by: Bk, Fn, Ju, N, Ne, Sm, Ss, Wal, Yo. 



f A list of abbreviations follows table 33. 



Table 32 

 Strains of guinea pigs in development 



Name or 



Symbol Synonym(s) 



Remarks 



ICRF 

 OM 3 



R 7 



R9 



ICRF/GP inbr: F 12 . origin: P. C. Williams, 1954, a heterogeneous (?) stock. 



charac: albino, some polydactylism. maintained by: Icrf. 

 inbr: F ? origin: J. B. Rogers, 1952, from a random-bred com- 

 mercial stock, charac: no toxemia of pregnancy, no spontaneous 

 tumors, does not reproduce well above 5000 feet, maintained by: 

 Rog. 



inbr: F ? origin: J. B. Rogers, 1941, from a random-bred stock. 

 charac: toxemia of pregnancy (15% incidence in late pregnancy, 

 during parturition, and 1 week post-partum), no spontaneous tumors, 

 life span 3+ years, maintained by: Rog. 



inbr: F ? origin: J. B. Rogers, 1941, from random-bred ancestry. 

 charac: 14% spontaneous tumor incidence in animals over 1095 days 

 of age, life span 4+ years, maintained by: Rog. 



