98 GENETIC STOCKS AND BREEDING METHODS 



Table 27 — Continued 



Name or 

 Symbol 



Synonym(s) 



Remarks 



PBR 



PHH 



RI 



RIET 

 RUS 



RIII 



RHI/Jax 



RIIIfB 



RIII-ro 



pBr 



pHH, high 

 blood-/>H 



Paris, R3 



Radium In- 

 stitute (Paris) 

 line III 



RHI/Wy R3 



RIIIX 



inbr (St): 56. genet: aabbpp. origin: Strong, from methyl- 

 cholanthrene-treated NH mice, charac: mammary tumors in 

 breeders, maintained by: St. 



inbr (We): 28. genet: aalnln. origin: from MacArthur outbred 

 stock, obtained from Butler, 1949. Selected for high blood pH, with 

 b x s mating, charac: blood pH 7.47; sex ratio 55% <$<$. Sex 

 ratio now 52% gg. Mean litter size at weaning 6.5. Over-all 

 fertility low. maintained by: We. 



inbr (We): 24. genet: aabblnln\a l a l bblnln (leaden brown, and leaden 

 brown-and-tan families), origin: same as PHH, selected for low 

 blood pH. charac: blood pK, 7.42 ; sex ratio 45% <$<$, now 42% £<$. 

 Mean litter size 5.7. Over-all fertility high, maintained by: We. 



inbr (Ly) : 43. genet: cc. origin: from noninbred "Princeton" 

 strain started in 1922 from 200 mice purchased from dealer. Inbred 

 by Lynch, giving rise to a high leukemia line B ( = PL) and a second 

 line A ( = PLA) with lower incidence, charac: few mammary 

 tumors, 80-90% leukemia, maintained by: Jax, Ly, Sp. 



inbr (Ly): 43. genet: cc. origin: see PL. maintained by: Ly. 



inbr (Jax): ? + 18. genet: cc. H-2 k . origin: Furth, 1928, from 

 unknown stock at Rockefeller Institute. He transferred stock to Oak 

 Ridge; to Jax at Oak Ridge's F 14 . charac: low incidence of leukemia, 

 higher after radiation, maintained by: Gif, Jax, Jb. 



inbr (Gw) : 48. genet: aabbcc origin: Gowen, from Webster's 

 resistant stock in 1936. charac: quite resistant to Salmonella typhi- 

 murium; unreliable to poor breeders, maintained by: Gw. 



inbr: 31 + . origin: Korteweg. maintained by: not reported. 



inbr (Rl) : 31. genet: a'a'ruruss. origin: from Holman Jan. 1948 

 (F 4 from Dunn's BT ruby x Holman's black piebald, shaker-1). 



MAINTAINED BY: Rl. 



inbr (Crgl) : ? + 25. genet: cc. origin: Dobrovolskaia-Zavadskaia, 

 Paris, 1928. charac: animals have milk agent; mammary tumor in 

 84% of breeders, 40% of virgins. Nonchromosomal resistance 

 factor against leukoses. Susceptible to pulmonary infection. Good 

 reproducers but bad mothers (cannibalism frequent), maintained 

 by: Crgl, Mr, Per, Rd, Rho. 



inbr (Jax) : 3 1 . genet : cc. origin : Dobrovolskaia-Zavadskaia. Sent 

 to Eisen, Eisen to Jax 1948. charac: fairly high incidence of mam- 

 mary tumors. Resistant to RHI/Wy transplantable tumors. Sus- 

 ceptible to skin ulcerations, maintained by: Gif, Jax. 

 inbr (Jax): 48. genet: cc. H-2'. origin: Dobrovolskaia- 

 Zavadskaia, to Curtin and Dunning, to Woolley before 1947. One 

 pair survived Bar Harbor fire; to Snell in 1950, to Jax in 1957 at F42. 

 charac: fairly high mammary tumor incidence, resistant to skin 

 ulcerations found in RHI/Jax. RHI/Wy transplantable tumors will 

 not grow in RHI/Jax. maintained by: Jax. 



inbr (Pu): 58. genet: cc. origin: RIII fostered on C57BL. 

 charac: does not have milk agent, but very sensitive to it. Mammary 

 tumors in breeders 3%. Fertile but poor mothers, maintained by: 

 Pu, Rd. 



inbr (Fa): ? + 29. genet: cc + ro. charac: ro segregates, main- 

 tained by: Fa. 



