GENETIC STRAINS AND STOCKS 

 Table 27 — Continued 



93 



inbr (Sn) : G18F5. genet: same as C57BL/10 except for substitution 

 of H-VA for H-3 a a. 



Remarks 



C57BR/cd C57 brown 

 subline cd, 

 BR 



C57BR/a- 

 AFu 



C57L C57 leaden, 



M, L, LN 



C58 



C58-wa 



DA 



DB 



inbr (Sn): G18F5. 



inbr (Gnu): N24. genet: aa + lu. origin: Green, lu obtained by 

 mutation in C3H/HeGn in 1950, continuously backcrossed into 

 C57BL/10JaxGn starting about 1950. charac: about 90% penetrance 

 of lu in heterozygotes. maintained by: Fo, Gn. 



inbr (Gn): N21. genet: aa + Ix. origin: Green, Ix obtained from 

 T. C. Carter, backcrossed continuously into C57BL/10JaxGn starting 

 about 1950. charac: about 70% penetrance of Ix in heterozygotes. 



MAINTAINED BY: Fo, Gn. 



inbr (Fa) : ? + 3 1 . genet : + wr, wrwr. origin : mutation in 

 C57BL/Fa circa 1955. maintained by: Fa. 



inbr (Sp) : 47. genet: aabb. origin: see C57BR/a and C57BR/cd; 

 all existing branches probably belong to one or the other of these 

 sublines, maintained by: Rl, Sp. 



inbr (Rr) : 100. genet: aabb. H-2 k . origin: Little, from same 

 $ 57 and 6* 52 that gave rise to C57BL, C57BR/cd, and C57L. Black 

 and brown lines were separated in first generation. C57BR/a was 

 separated from other brown lines in ninth generation, charac: low 

 mammary tumor incidence, maintained by: Ms, Rr. 

 inbr (Jax) : 101. genet: aabb. H-2 k . origin: Little, from same $ 

 57 and 6* 52 that gave rise to C57BL, C57BR/a, C57L. Black and 

 brown lines were separated in the first generation. Subline cd was 

 established in generation 13 from a cross of two brown branches, one 

 of which had previously given rise to line C57BR/a. charac: low 

 mammary tumor incidence. Hepatomas 14% in o*6*- maintained by: 

 Gif, Jax, Jb, Lab. 



inbr (Rr): N15. genet: AabbFufu. origin: C57BR/aJRr. charac: 

 70% penetrance of Fu. maintained by: Rr. 



inbr (Jax): 77. genet: aabblnln. H-2 b . origin: J. Murray, 1933, 

 mutation in generation 22 of a C57BR subline of which the non- 

 leaden (brown) branch is now extinct. Stock maintained by Cloud- 

 man, to Heston, 1938, back to Jax, 1947, at F 45 . charac: low 

 mammary tumor incidence. Hematocrit value extremely high. 

 maintained by: Anl, De, He, Jax, Jb, Lab, Mc, Ms, N, Rl, S. 



inbr (Jax): 111. genet: aa. H-2". origin: MacDowell, 1921, 

 from mating of littermates ? 58 x (J 52 of Miss Lathrop's stock. 

 6* 52 mated to littermate ? 57 gave rise to C57BL, C57L, C57BR/a, 

 and C57BR/cd. charac: high leukemia, maintained by: Cbi, Ha, 

 Hd, Icrc, Jax, Ms. 



inbr (Ha): 22 since mutation, genet: aa + wa. origin: spon- 

 taneous waved mutation in C58/MdHa in 1952 (do not know which 

 "waved"), maintained by: Ha. 



inbr (Jax): 48. genet: cc. origin: Hummel, 1948, 1 6* and 3 $$ 

 born to nonpedigreed Swiss $ with mammary gland tumor, charac : 

 medium mammary tumor incidence, many partitioned vaginas. 

 maintained by: Hu, Jax. 



inbr (Sp): ? + 18. genet: aabbdd. origin: Murray, C57BL $ x 

 DBA 6*) backcrossed eight generations to DBA <$, then inbred. To 



