92 GENETIC STOCKS AND BREEDING METHODS 



Table 27 — Continued 



Name or 

 Symbol Synonym(s) 



Remarks 



C57BL 



C57 black 



C57BL/6 B/6, B6, B 



C57BL/ C57 black 

 lOJax subline 10, 



B/10, BIO 



C57BL/ B/lOSc 

 lOSc 



C57BL-« ( 



C57BL- 

 fl'2 



C57BL-6 

 C57BL/Ks 



C57BL/ 

 10-//- \ d 



C57BL/ 

 10-//-2" 



C57BL/ 

 \0-H-2 d N 



C57BL/ 

 10-//-2 / 



C57BL/ 

 10-//-2' 



B10.BY 



B10.D2 



III (Hi 



B10.M 



B10.Y 



inbr (Cbi): 60. genet: aa. origin: Little, 1921, from heterozygous 

 sib pair, $ 57 x o* 52, from Miss Lathrop's stock. $ 52 mated to 

 littermate $ 58 gave rise to strain C58. See also C57BL/6, C57BL/10, 

 C57BT/a, C57BR/cd, and C57L. charac: very low mammary 

 tumor incidence; no MTI. Resistant to mammary and ovarian 

 tumor induction by chemical carcinogens. Sporadic juvenile hair 

 loss. Eye abnormalities in about 10% of animals; incidence varies 

 in different sublines. Large numbers of skeletal variants. Various 

 types of internal tumors. Susceptible to lymphoma induction by 

 X ray. maintained by: Am, Ber, Cbi, Crgl, De, Fa, Fn, Fr, G, Ge, 

 Gif, Go, Gr, H, Ha, He, Ka, Kn, Lab, Mr, Mv, Not, Oci, Per, Pi, 

 Pu, Rd, Rij, Rl, S, Sp, St. 



inbr (Jax) : 61. genet: aa. origin: see C57BL. Sublines 6 and 10 

 separated prior to 1957. charac: differs from C57BL/10 in incidence 

 of eye defects. Has 6% lymphocytic leukemia and 9% reticulum- 

 cell sarcoma, maintained by: Anl, Chr, Gif, Jax, Lab, Ly, Mas, 

 Ms, N, Sb, Sfd, Ss, We. 



inbr (Jax) : 66. genet: aa. Histocompatibility-2 allele in C57BL/ 10, 

 and probably all other sublines unless otherwise indicated, H-2 b . 

 origin: see C57BL. Sublines 6 and 10 separated prior to 1937. 

 charac : differs from C57BL/6 in incidence of eye defects. Comparison 

 of behavior traits of C57BL/10Sc and C57BL/10Jax showed differences. 

 maintained by: Ch, Fo, Gn, Jax, Jb, Rl. 



inbr (Sc) : 69. genet: aa. origin: same as C57BL/10Jax. Some 

 of original stock from Little to Scott, charac: similar to C57BL/10Jax. 

 On basis of behavior tests using both C57BL/10Sc and C57BL/10Jax 

 differences were apparent in the two groups, maintained by: N, Sc, 

 Sn. 



inbr (H) : ? + 13 since mutation, genet: a l a x aa. origin: spon- 

 taneous mutation to a 1 in C57BL/H in 6th generation at Harwell. 

 maintained by: H. 



inbr (H) : ? + 12 since mutation, genet: a l a l . origin: derived 

 from C57BL/H-a'. maintained by: H. 



inbr (Bnd) : 20 + . genet: aabb. origin: mutation from B to b in 

 1956 in Barnard Lab. charac: large viable litters; high fertility. 

 maintained by: Bnd. 



inbr (Ks): 39. genet: aaH-2 d H-2 d . origin: derived from non- 

 pedigreed mice bred at Jax, sent to Sloan-Kettering Inst., 1947, and 

 returned to Jax 1948. charac: resistant to C57BL/6 tumors E 0771 

 and C 1498. maintained by: Ks. 



inbr (Sn) : G18F5. genet: same as C57BL/10 except for substitution 

 of//-l d (or//-l 6 ) for//-l c . 



inbr (Sn): G12F3G6F3G4F0. genet: same as C57BL/10 except 

 for substitution of H-2 d for H-2". 



inbr (N): 28. genet: aa. origin: Borges to NIH 1953 at F 12 . 

 charac: resistant to C57BL/10 tumors, maintained by: N. 

 inbr (Sn): G12F13G4F1. 



inbr (Sn): G14F10G4FI. 



