628 



SUBJECT INDEX 



Anemias — continued 



W-series, 224 

 Anencephaly, 191, 238 

 Aneuploidy, 416 



of cells in culture, 507 

 Animal-breeding rooms, reverse-lighting pat- 

 terns in, 154 

 Animal mutations chemically produced, 154 

 Anomalies 



metabolic in mice, 466 



of urinary tract, 238 

 Anophthalmia, 189 

 Antibodies, 348 



absorption of in vivo, 376 



cellular, 375 



cytotoxic, 429 



fluorescent, 379, 463 



labeled, 378, 463 



radioactive, 463 



reagents, preparations of, 354 



tumor, 269 

 Antibody 



formation, 422 



production, differences in between strains, 

 379 



titer, 193 

 Antigen-antibody reactions, 347 

 Antigenic 



differences, 193 



and malignancy, 453 



simplification in transplanted tumors, 425 



specificity 



genetic control of, 417 

 loss of, 432 

 Antigens, 348 



clearance of labeled, 363 



coupled with red cells, 367 



histocompatibility, 465 



macromolecular, 348 



molecular, 348 



soluble, 366 



tumor-specific, 460 



univalent, 349 

 Antiglobulin tests, 361 



Antimetabolites, resistance of cells in vitro to, 423 

 Antisera, procurement of, 350 

 Array, frequency, 42 

 Arthropods, susceptibility to viruses, 402 

 Ascites 



conversion, 433 



form of tumor cells, 423, 468 

 Aspergillus, 161, 434, 460 

 Assortment, random, 48 

 Atavistic digits, 176 

 Atomic recoil, 130 

 Attitude, genetic variance, 216 

 Audiogenic seizures, 230, 285, 287 

 Autonomy of tumors, 441 

 Autosomal linkage groups, 76 

 Auxotrophic mutants, selection of, 451 

 Average rate fixation of loci, 55 



Avian 



embryos, use of for heterologous graft, 327 

 malaria, 403 

 Avidity, 350 



Backcrosses, 4, 5, 58 

 double, 57 



genotypes among offspring, 61 

 method of testing mutations, 137 

 single, 57 

 Backcross system, 18 



generation matrix of, 20 



generations required to obtain given percent- 

 age of incrosses, 2 1 

 mating types and their probabilities, 19 

 of mating, 53 

 probability of 



heterozygosity in, 70 

 incrosses for, 20 

 Bacteria, selection of drug resistant, 408 

 Bacteriophages, temperate, 459 

 Balance, genie, 508 

 Barking, variations in, 286 

 Barrett-Deringer 



change in transplanted tumors, 426 

 phenomenon, 467 

 Barrier, uterine, 241 

 Bedding for mice, 541, 545 

 Behavior 



development of, 286 

 influences of environment on, 287 

 measurement of, 288 

 Behavioral 



differences, 283 

 pattern, 284 



relationship to genetic variation, 285 

 unit of, 284 

 dominance, 402 

 genetics, 295 



developmental threshold in, 296 

 methodology of, 293 

 pattern 



frequency of, 288 



genotypic versus phenotypic mutation in, 



290 

 intensity of, 288 

 latency of, 288 

 mechanism of, tests for, 292 

 phenotypes, 292, 295 

 traits, 148 



variation, relationship to genetic variation, 

 285 

 Behavioral differences, 283-293 

 Belts of radiation, 129 

 Bibliography, 571-621 



subject strain, 51 1 

 Biochemical 



effects of teratogens on development, 240 

 pathways 



genetics of, 297 



relation of genes to behavior, 292 



