630 



SUBJECT INDEX 



Chinese hamsters, 189, 471, 473, 493, 498, 507, 

 509 

 cytologic characteristics of, 498 

 diabetes mellitus in, 267 

 idiogram of, 483 

 pancreatic tumors in, 267 

 pituitary tumors in, 267 

 sex chromosomes of, 496 

 strains of, in development, 1 16 

 tissue cultures, 485 

 Chi-square, 58, 59 



for linkage for three kinds of matings, 59 

 for segregation at individual loci, 59 

 heterogeneity, 73 

 Choice of suitable breeding system, 39 

 Chromatography 



cellulose ion-exchange, 377 

 column, 307, 321 

 paper, 340 

 Chromosomal 

 breaks 



and abnormal embryonic development, 152 

 and restitution, kinetics of, 131 

 changes in transplanted tumors, 433 

 markers, 452 



in tumors, 446 

 morphology, 423 

 Chromosomes 



identification of individual chromosomes, 494 



layout for preparation of, 490 



mean length of heterozygous, 22 



pattern of alteration of numbers in vitro, 



507 

 preparation of, utilizing vinkaleukoblastine, 



475 

 sex, 494 



Chinese hamster, 496 

 staining, 480 

 techniques 



for permanent preparations of, 484 

 for preparation, 472 

 unsquashed preparations of, 491 

 use of 



colchicine in preparation of, 473, 501 

 hyaluronidase in preparing, 479 

 ribonuclease in preparing, 479 

 Chronic exposures to radiation, 130 

 Cleft 

 lip, 243 



palate, 238, 241, 243, 244, 245 

 Clones, 450 

 Cloning, 462 

 single-cell, 468 

 techniques of, 461 

 Clustering of malformations, 243 

 Coat color 



environmental effects on, 169 

 of guinea pigs, factor interactions in, 161 

 Cobalt-60, 128 

 Code for marking ears, 523 

 Coefficient of inbreeding, 44, 55, 194 



Coisogenic color lines 



development of, 325 



utilization in studying genie interactions, 

 326 

 Colchicine, use of in chromosomal preparations, 



473, 501 

 Colicinogenic factors, 459 

 Collection of blood in mice, 558 

 Color 



factors and activity of tyrosinase, 170 



interactions, 172 



lines, coisogenic 



development of, 325 



utilization in studying genie interaction, 

 326 



stocks, development of inbred, 324 

 Column chromatography, 307, 321 

 Comb and size of, in chickens, 271 

 Combinations 



of locus control and relationship, 5 



of teratogens, effect of, 241 

 Committee on Standardized Genetic Nomen- 

 clature for Inbred Strains of Mice, 83 

 Comparison of mortality of mice and man, 147 

 Complement fixation, 370 



test, 376 

 Concept of thresholds, 293 

 Congenital deformities produced by acute X 



irradiation, 153 

 Constant effects, 1 79 

 Containers, shipping, for mice, 555 

 Contamination, cellular, of tissue cultures, 493 

 Continuously distributed traits, 296 

 Control, karyotypic, 472 

 Control of the literature on genetics of the 



mouse, 511-516 

 Conversion 



ascites, 443 



lysogenic, 447, 456, 459 

 Correlated changes in rates of hormonal secre- 

 tion, 273 

 Correlation 



between weight and size of litter in guinea 

 pigs, 281 



phenotypic, between members of families, 203 

 Corti's organ, differentiation of, 219 

 Cosmic 



particles, 129 



radiation, 129 

 Counts of chiasmata, 76 

 Coupling phase of linkage, 57 

 Covers for cages for mice, 549 

 Crest, neural, 34 

 Cross-backcross-intercross system, 27, 28, 53 



cross-generation matrix for, 30 



cycle matrix for, 30 



cycle matrix of, 31 



generation matrix of, 31 



mating, 3, 5 



intercross generation matrix of, 31 

 types and their probabilities, 27 



