SUBJECT INDEX 



631 



Cross-backcross-intercross system — continued 



probability 



of heterozygosity, 30 

 of incrosses for, 29 



probabilities of mating types, 29 

 Crosses, 4 

 Crossing over, 77 



in H-2 locus, 466 



somatic, 410, 460, 467, 468 

 in transplanted tumors, 433 

 Cross- intercross system, 5, 22, 23, 53 



cycle matrix of, 25 



mating types, 22 



matrices for, 26 



probabilities of various mating types, 24 



probability of heterozygotes, 24 

 Crystallography and solubility of hemoglobin, 



311 

 C-terminal analysis, 316 

 Cultures, tissue 



cellular contamination, 493 



Chinese hamster, 485 

 Culture tubes, 504 



cytologic preparations for, 504 

 Cumulative 



action of multiple alleles, 182 



effects, 179 

 Current applications of a method of transplanta- 

 tion of tissues into gland-free mammary 

 fat pads of mice, 565-569 

 Cystamine, 149 

 Cysteamine, 149 

 Cysticerus fasciolaris, relationship to sarcomas in 



rats, 253 

 Cytocidal interaction of tumor viruses, 447 

 Cytogenic analysis, 469-507 

 Cytogenic analysis of radiation effects, 143 

 Cytogenetics, references and manuals useful in, 



503 

 Cytologic 



characteristics of Chinese hamster, 498 



preparations, culture tubes for, 504 

 Cytotoxic 



antibodies, 429 



technique, 375 



tests, 378 



in non-//-2 systems, 378 



Deformities, congenital, produced by acute X 



irradiation, 153 

 Degree of genetic determination, 194, 216 

 Demes, 185 



Denaturation, alkali, 311 

 Deoxyribonucleic acid, 217 

 Dependence, hormonal, 441, 468 

 Deringer-Barrett change in transplanted tumors, 



426, 467 

 Detection of linkage between ru andje, 66 

 Determination, genetic, 194, 195 

 experimental design, 196 



Deuterium, introduction into biological systems, 



130 

 Deuterons, 129 



Development, immunologic aspects of, 240 

 Developmental 



method for studying behavior, 286 



threshold in behavioral genetics, 296 



stage at which teratogen is used, 236 

 Diabetes mellitus, 189 



in Chinese hamsters, 267 

 Diagram 



gamete, 45 



zygote, 44 

 Dibenzanthracene, 255 

 Differences 



antigenic, 193 



behavioral, 283 



in stability of hemoglobin, 322 

 Differential selection, 211, 213 

 Differentiation 



alteration of, by genes, 222 



of cellular function, 464 

 Digits, atavistic, 176 

 Dilute, lethal, 230 

 Diploid karyotype, retention of, 471 

 Diploidy, 507 



Discrepancy between action of teratogenic 

 agents in humans and laboratory 

 animals, 237 

 Disease resistance, transmission of, 386 

 Dispenser, food, 552 

 Disturbed segregations, 61 

 Dominance, behavioral, 402 

 Dominant 



lethal effect of hypoxia, 148 



lethals from radiation, 135 



mutations, 136 



spotting (W v ), 70, 71 



visible mutation, 140 

 Dopa reaction, 171 

 Dose 



effect of on mutation rate, 141 



rate of radiation, 142 

 Dosimetry, 128 

 Double backcross, 57, 58 

 Double heterozygote, 57 

 Double matings, 388 



technique of, 402 

 Double recombinant, 75 

 Drift 



genetic, 267 



random, 187, 192 

 Drosophila, 48, 55, 129, 131, 137, 141, 142, 144, 

 152, 154, 185, 290, 292, 341, 400, 460, 

 508 



gynandromorphs, 419 



somatic crossing over in, 410 



somatic mutation in, 421 

 Drug resistance, 460, 468 



and hormonal independence, 437 



and karyotype, 440 



