634 



SUBJECT INDEX 



Guinea pig — continued 



correlation between weight and size of litter, 

 281 



environmental effects on coat color, 169 



established strains of, 1 12 



eumelanin 



and phaeomelanin in, 163, 164 



in at birth and six months later, 165 



factor interactions 



between hair direction and white forehead 



spot, 173 

 in coat color, 161 



forehead spot in, 175 



hair direction in, 172 



homology, 178 



lymphosarcomas in, 254 



mean intensity index for various genotypes of 

 coat color, 166 



mean quality index for various genotypes of 

 coat color, 166 



opposite direction of effect in different com- 

 binations, 180 



pigment-cell studies in, 333 



Polydactyly in, 176, 293 



replicative homologs, 178 



selective value, 181 



spotting, 162 



stocks of, of genetic interest, 1 13 



strains of, in development, 1 12 



symbols for designating substrains of, 113 



types of genie interaction in, 179 

 Gynandromorphs, 414 



in Drosophila, 419 



H-1 locus, crossing over in, 466 

 Hagedorn effect, 186 

 Hair direction 



factor interactions in, 173 

 in guinea pigs, 172 



pleiotropic effect of, on white forehead spot, 

 173 

 Half molecules, of hemoglobin dissociation, 310 

 Hamsters 



cancer of pancreas in, 267 

 Chinese, 189, 471, 493, 498, 507, 509 

 cytologic characteristics of, 498 

 diabetes mellitus in, 267 

 idiogram of, 483 

 sex chromosomes, 496 

 strains of, in development, 1 16 

 tissue cultures, 485 

 pituitary tumors in, 267 

 symbols for designating substrains, 1 17 

 Syrian, 471, 473 



established strains of, 114 

 stocks of, of genetic interest, 116 

 strains of, in development, 115 

 Handling of mice, 543 

 Haploidization in molds and somatic crossing 



over, 412 

 Harderian-gland tumors, 250 



Harelip, 178 



Hemagglutinating materials, diverse, 351 

 Hemangioendothelioma, 250 

 Hematocrit determination, 561 

 Hematopoietic tissues, 373 



study of, 562 

 Hemes, 322 

 Hemoglobins 



chemical methods for analysis of, 314 



differences 



in segregation patterns, 321 

 in stability, 322 



dissociation into half molecules, 310 



in mice, analyzed by "fingerprinting," 319 



mammalian, 299 



physical methods for analysis of, 300 



physical methods for study, 300 

 alkali denaturation, 31 1 



column chromatography, 307 



crystallography and solubility, 31 1 

 electrophoretic analysis of, 300 

 moving-boundary electrophoresis, 301 

 ultracentrifugation, 309- 

 zone electrophoresis, 302 



solubility, 314 



structure of, 218, 300 

 Hemoglobinopathies, human, 224 

 Hemolysis, 349, 360 



test systems, 360 

 Hepatomas, 249, 265 

 Hereditary sterility from radiation, 134 

 Heredity, infective, 422, 461 



and viral tumors, 446 

 Heritability, 194, 198, 212, 216 



offspring-parent regression, 201 



sib analyses, 205 



standard error of, 209 

 Heterochromatin, 494 

 Heterogeneity 



chi-square, 72 



estimation of, 70 

 Heterogenous strains, 194 

 Heterosis, 214 

 Heterozygosis, 32, 44 



forced, 257 



limiting ratio of, 49, 53 



ratio of, 48 



relative, recurrence equation for, 49 



residual, and resistance to induced sarcomas, 

 436 

 Heterozygosity, probability of, 4 



cross-backcross-intercross systems, 30 



cross-intercross system, 24 



with heterozygosis forced by backcrossing, 34, 

 35 



with heterozygosis forced by intercrossing, 37, 

 38 

 Heterozygotes 



double, 57 



high selective value for, 53 

 Heterozygous tumors, behavior of, 429 



