636 



SUBJECT INDEX 



Inhibition 



enzymatic, 367 



systems with soluble antigens, 366 

 Instinct, broody, 278 

 Intensity of behavioral pattern, 288 

 Intensity-stimulus, relationship between, in two 



populations, 289 

 Interaction 



effects, nonadditive, 161 



genie, in evolution, 183 



of genes and teratogens, 244 



types of, 179 

 Intercross generation matrix, 31 

 Intercrosses, 4, 57, 58 



in repulsion, 59 

 Interdemic selection, 192 

 Intermediate optima, 191 

 Internal emitters, 129 



International cooperation in genetic studies, 151 

 International rules of nomenclature for mice, 



517-521 

 Interstitial cell tumors of testis, 250 

 Intrademic selection, 185 

 Intrauterine variables related to malformations, 



243 

 Ion-exchange absorption, 307 

 Ionization, 130 



density, 141 

 Iron mordant, 488 

 Isoantigenic 



divergence, 454 



markers, 417, 468 



variants from F \ tumors, 434 



variation, 460 

 Isoantigenicity of induced tumors, 426 

 Isoantigens, 468 



and transplantation characteristics, 4-24 



of cells in culture, 463 

 Isoimmunization, fetal-maternal, 465 



Kappa particles in Paramecium, 262 

 Karyotype, 494 



and drug resistance, 440 



diploid, retention of, 471 



variation, 508 

 Karyotypic control, 472 



Kidney, absence of and Short- Danforth gene, 222 

 Klinefelter's syndrome, 415 



Labeled 



antibodies, 378, 463 



antigens, clearance of, 363 



cells, elimination rates of, 363 

 Labor of measurement, 202 

 Lactation in cattle, 273 



rank order and, 274 

 Latency of behavior, 288 



Layout for preparation of chromosomes, 490 

 Leaky enzyme, 230 

 Lethal (s), 55 



dominant, from radiation, 135 



Lethal (s) — continued 

 linked procedure, 138 

 mutations, 136 

 sex-linked, 140 

 Leucocyte counts, 562 

 Leukemia, 249, 260, 268 

 genetics of in mice, 254 

 genetic studies on, 253 

 murine, 423 

 resistance to, 253 

 Liesegang phenomenon, 376 

 Limiting ratio of heterozygosis, 49, 53 

 Linear accelerator, 129 

 Linear order of loci, 73 

 Line breeding, 4 

 Linkage 



chi-square, for three kinds of mating, 57 

 coupling phase, 57 

 crosses, proportion of offspring in, 62 

 detection of, between ru andje, 66 

 groups, 76 



autosomal, 76 

 map, 56, 76 



distances between loci, 77 

 of the mouse, 77, 78 

 methods for testing, 56 

 nonrandom associations, 194 

 of ru and je, 70 

 repulsion phase, 57 

 sex, 77 



stocks for testing, 75, 76 

 testing segregations and detecting, 58 

 types of matings useful in determining, 56 

 Linked genes, order of, 56 

 Linked lethal procedure, 138, 153 

 Linked locus, analysis of gametic pairs with 



respect to, 47, 50 

 Literature, control of, on genetics of the mouse, 



511 

 Litter 



correlation between weight and size in guinea 



pig, 281 

 reduction of size following radiation, 139 

 size of, 271, 281 



and hormonal secretion, 273 

 size, variance of in mice, 208 

 Liquid nitrogen, use of as refrigerant for cells in 



vitro, 510 

 Loci 



average rate of fixation of, 55 

 linear order of, 73 

 Locus, piebald, mutation rate of, 138 

 Lung 



fetal transplants of, 259 

 tumors of, 249, 254, 258, 259, 264, 266 

 estimating susceptibility genes for, 248 

 estimation of number of genes, 254 

 in mice, 251 



method of induction with carcinogens, 255 

 production of 



with nitrogen mustard, 255 



