THE GOLGI MATERIAL 



77 



an acid dye, in the Golgi region of liver and kidney cells.^ The chromo- 

 phihc girdle on the secretion droplet is regarded as a bit of the Golgi 

 material. The gradual disappearance of this girdle as the droplet enlarges 

 suggests an actual transformation of the Golgi substance into the secre- 

 tion (Jacobs, 1928, 1929). 



The view of Morelle (1923, 1926, 1927) is that the Golgi region, or 

 "Golgi spot," in cells of the pancreas is a formless mass of substance 



Fig. 38. — Formation of lipoidal secretion droplets by scattered Golgi bodies in sebaceous 



gland of mouse. (After Ludford, 1925.) 



■■■K 



with fairly dejfinite limits but without the organization shown in fixed 

 preparations. The secretion droplets are formed within it, one of the 

 materials for the synthesis being furnished by chondriosomes which 

 appear to enter the Golgi region after being elaborated 

 in the "basal protoplasm" (Fig. 39). The chromo- 

 philic girdle is attributed to unequal impregnation of 

 the secretion droplet. Saguchi (1920) had previously 

 described the formation of prozymogen granules from 

 chondriosomes in this " secretogenous area" of the cell. 

 Ludford (1928) suggests that a synthesis through 

 enzyme activity occurs at the surface of the chondrio- 

 somes and that the product is concentrated in the form 

 of droplets at the surface of the Golgi material. 



Another interpretation is that of Parat and his 

 collaborators.'^ According to these workers, the cyto- 

 plasm of the animal cell includes only two constant pancreas of ^rog, 

 formed elements: chondriosomes and vacuoles. In showing elongated 



1 1 11 ,1 ic /~i 1 • ») • J. r r chondriosomes in 



gland cells the "Golgi zone" consists of a group of middle portion of the 

 secretory vacuoles, which stain with neutral red and cell where the secre- 



1. . ,, • 1 J. r •^^ ^ n i r j. i tion is produced. 



lie in the midst oi an ill-denned mass oi cytoplasm con- (^y^g^ Morelle, 1923.) 

 taining "diffuse lipoids" and "active mitochondria" 

 Fig. 40, B). It is not an organ with definite morphology, but a region 

 in the cytoplasm where active secretory vacuoles accumulate and attract 

 the other elements about them. The net-like aspects so often described 



6 Jasswoin (1925), Nassonow (1926), Ludford (1928). 

 ^ 1924-1930. See especially Parat (1928). 



