Subject Index 



253 



Osier's disease, S"), 105 

 Osteoporosis, calciimi nietal)oIisin 

 in, 110, IKi-ns, 121, 122 

 senile, incidence, 125 

 Ovary, aiieing of, 141-159 



age changes in sensitivity to 



hormones, 142-14() 

 isolated, long storage of, 1 05-100 

 life-span of cells, 142 

 ])otential immortality, 157-159 

 transplantation, 150-152, 154-157, 



158-159 

 tumours in grafted, 153, 154 

 Overnutrition (see also Nutrition) 

 of cliildren as cause of ageing, 194- 

 199 

 Ovum, age changes, 149-150 

 life-span, 147-149 

 maternal age and, 172 

 transplantation, 150 

 Oxygen partial pressure, loAvered, 

 effects, 08 

 quotient of aortic tissue. 70, 78 

 uptake in age, 200, 207 



Palmar erythema, 82 

 Pancreas, elastase in, 99, 108 

 Parabiosis in ageing research, 170, 

 180 

 in retarded rats, 30 

 Pdramecium, 55 

 Parental age, importance, 147, 



238-241 

 Pathogenesis of arteriosclerosis, 28 

 Pathological basis of ageing, 10-23 

 changes in brain, 34, 35, 30, 49 

 in cells, 54 

 Pathology at autopsy, lack of 

 findings, 20 

 specific, of age, 54 

 in Swiss centenarians, 10, 17 

 Peptic ulcer, incidence in aged, 18, 19, 



20 

 Permeability of membranes, 09-75, 



70, 77, 78 

 Personality changes, 42-44 

 Phosphate absorption, 124 

 Pigmentation of cell, 53, 54 

 Pigs, life-span changed bv nutrition, 



188-190, 192 

 Pneumonia, incidence in aged, 18, 



19, 20 

 Populations, homogeneity of, 204 

 Poultry, usefulness in ageing 

 research, 177 



Pre-senile dementia, 44, 45, Ki 

 Preparation of elastin, 90, 91 

 Preservation ol" skin by free/ing, 170 



of tissues hy freezing, 1(>2-1()9, 171 



of whole body by freezing, 107- 



1 09 

 Pressure, atmospheric, adaptation 



to, 24 

 Prisoners, usefulness for ageing 



research, 184 

 Proteins of bodv, age on structure, 



103, 104 

 Protozoa, r^o, 180, 187, 188, 191 

 Psychological aspects of ageing, 



30-39, 209-213, 214, 215-218 



changes, sex difference, 214 



tests after steroid administration 

 in aged, 137, 138 

 Psychoses, adrenocortical function 



in, 219-230, 237 



senile, 44 

 Puberty, onset as criterion of 



maturity, 202-203 

 Pulmonary artery, elastin content, 

 92, 93, 94 



function, changes with age, 58-05, 

 00 



Rabbits, usefulness in ageing 



research, 181 

 Rats, calcium metabolism, 111-114, 

 124, 125 



emphysematous broncliitis in, 07 



ieai'ning experiments, 215 



life-span, 179, 180 



usefulness in ageing research, 178 



vitamin D requirement, 124, 125 

 Red cell regeneration, 24 

 Regression, mental, in senescence 



33, 34 

 Reproduction, effect of transplanta- 

 tion of ovary, 158, 159 

 Reproductive capacity, 11 



as criterion of maturity, 202, 203 



cycle in retarded rats, 30 



life, duration in monkeys, 145, 14() 

 Reserve, fvmctional, 55 



tissue, 55 

 Resistance to infection as measure 



of senescence, 

 Respiratory disease, incidence in 



aged, 18, 19, 20 



function, changes with age, 58-()5 

 Retardation of m.aturation, 27, 28, 



29, 30, 201 



