Adrenal Activity in Aged Schizophrenics 221 



age categories. The l)asal values for the young groups are 

 ahiiost twice as great as the corresponding values for the old 

 groui)s. This is to be expected on the basis of the greater 

 muscular mass of the young subjects, although a renal factor 

 may be implicated. The normal subjects, both young and 



Table I 



Mean Creatinine Values for Young and Old Normal and Schizophrenic 

 Men Durinc; ACTH and Glucose Tolerance Tests 



N.B. Raised figures indicate nuinber of subjects. 



old, excrete slightly more creatinine in the basal state than the 

 corresponding patient groups, but the difference is statisti- 

 cally significant only between the two groups of young 

 subjects. 



The administration of ACTH results in no essential change 

 in the values for the younger groups but does show a definite 

 increase in the amounts of creatinine excreted in the two 



