224 Freeman, Pincus, Elmadjian and Romanoff 



to noon there is a decrease of 21 per cent in the eosinophil 

 count. 



The lymphocyte values (Table III) likewise show no sig- 

 nificant differences either in initial or in the post-injection 



Table III 



Values for Bi^ood and Urinary Metabolites in Elderly Normal and 

 Schizophrenic Men During ACTH Test 



♦Statistically significant difTerences between control values in the two groups. 



♦♦Statistically significant differences between the changes in the 2 or 4 hour values from the 

 basal levels between the two groups. 



N.B. Raised figures represent number of cases. 



values between the normal and the schizophrenic men. This 

 ne^yative finding has also been noted in younger groups of 

 subjects (Hoagland, et al., 1953). Ageing apparently does 

 not affect the lymphopenic response to ACTH, as both 

 Solomon and Shock (1949) and Pincus (1950) have found. 



In regard to the 17-ketosteroid/crcatinine ratios (Table III) 

 the basal levels of the patients are higher than those of the 



