HISTORICAL 7 



neglected. The realization that the cortex of the adrenal, 

 rather than the medulla, was vital to the organism soon turned 

 increasing attention to this part of the gland. With the ad- 

 vance of Endocrinology during recent years, the adrenal has 

 shared in the intensive study which has been applied to the 

 glands of internal secretion. Although the function of the 

 glands is still a mystery and the product elaborated by the 

 cortex still unidentified, much progress has been made. The 

 field has been sufficiently clarified to reveal the problems open 

 for investigation and the prospects of their solution. The 

 preparation of extracts which are capable of furnishing a com- 

 plete replacement therapy in the adrenalectomized animal has 

 opened new fields of investigation and supplied a new thera- 

 peutic agent for the treatment of human disease. 



