338 CLINICAL CONSIDERATIONS 



in the next chapter. Malignancy of the cortex proper (i.e. 

 of the interrenal tissue) does not give rise to virilism or to any 

 abnormality of the reproductive system. These tumors rarely 

 give rise to Addison's disease for the rapidity of their growth 

 and ready metastasis lead to death from carcinomatosis before 

 sufficient destruction of the cortex has taken place to manifest 

 the symptoms of Addison's disease. 



OTHER TUMORS 



The tumors described in the present and following chapters 

 are derived from tissues specific to the adrenal glands. Other 

 tumors may arise, of course, from the connective tissue, smooth 

 muscle, or blood vessel elements, but such tumors are exceed- 

 ingly rare. Fibroma, myoma, lipoma, hemangioma, lymph- 

 angioma, fibroxanthosarcoma, and sarcoma have been de- 

 scribed. Many tumors erroneously described under these 

 terms belong to the groups of tumors described in the pre- 

 ceding sections. 230 



