EFFECTS ON THE SPINAL CORD 



20I 



In pigs placed on a ration of wheat, etc., Hart, Miller and McCollum ('16) 

 obtained nervous symptoms and lesions resembling those of beriberi. The 



Fig. 63. — Nerve cells from the ventral horn of the spinal cord in fowls (Giemsa blood stain). 

 The nucleus, n, is indicated in each, a, cell from normal animal, showing Nissl bodies; b, c, 

 cells from fowl with polyneuritis (beriberi) after 24 days on polished rice diet. The nucleus 

 has degenerated; the Nissl bodies have disintegrated, and the stainable substance is collected 

 in irregular masses at one side of the cell. (Vedder and Clark '12.) 



Fig. 64. — A portion of a cross section of the ventromarginal column of the spinal cord in a 

 fowl with polyneuritis (beriberi) on a polished rice diet. Stained with hematoxylin and acid 

 fuchsin. /, /, nerve fibers in advanced stages of degeneration. (Vedder and Clark '12.) 



Fig. 65. — Sciatic nerve fiber (teased preparation) from fowl with polyneuritis (beriberi) on 

 polished rice diet. Shows advanced degeneration, with disintegration of the axone, a. Hema- 

 toxylin and acid fuchsin stain. (Vedder and Clark '12.) 



anterior horn cells and nuclei appear shrunken and degenerated; the Nissl 

 granules indistinct and the cytoplasm homogeneous. They considered the condi- 



