434 INANITION AND MALNUTRITION 



projections of lipoid-containing cells later extended down to the deeper layers 

 of the cortex. Hojer ('24) found a simple (cortical) atrophy, at first in 

 connection with hyperemia. 



Bessesen ('23) made an extensive study of the weights of the suprarenal 

 glands in guinea pigs at various stages of scurvy (Table 12). After 5 days on 

 scorbutic diet, the suprarenals averaged 8.1 per cent above normal; at 10 

 days, 7.4 per cent below normal; at 15 days, 9 per cent above normal; at 19 

 days (beginning scurvy), 78.8 per cent above normal; and at death from scurvy 

 (21-54 days), 270.1 per cent above normal (for corresponding final body 

 weight). In another group of guinea pigs which had recovered from scurvy 

 by addition of orange juice to the diet, the suprarenal glands still averaged 

 29 . 3 per cent above normal. 



During aqueous inanition, on a dry diet, Kudo ('21) found in adult albino 

 rats of the acute thirst series, with body loss of 36 per cent, a loss in the supra- 

 renals of 21.3 per cent; and in the chronic thirst series, with body loss of 52 

 per cent, a loss of 27.1 per cent in the suprarenals; while in a rat on total inani- 

 tion, with loss of 47 per cent in body weight, the suprarenals lost 16.6 per cent 

 (Table 9). In young albino rats held at constant body weight by a relatively 

 dry diet for various periods beginning at about four weeks of age, Kudo ('21a) 

 found a progressive increase in the suprarenals, amounting to 71.4 per cent 

 for the males and 66.2 per cent for the females, in the groups tested for the 

 longer periods (Table 10). Thus the results are somewhat similar to those 

 during total (complete or incomplete) inanition. 



