732 Experiments 



denly. Is in quite strong convulsions. White foam very abundant in 

 the mouth. 



Rectal temperature 37°. 



At 3:45, drew a little blood for sugar analysis; the animal is in 

 convulsions y 



At 4 o'clock, the animal is calm; respiratory rate 14, pulse 60. 



From 4:12 to 4:27 (15 minutes), made to breathe in the same 

 quantity of pure air as above b 



The respirations remain calm the whole time. 



At 5 o'clock, rectal temperature still 37°. The animal, when put 

 on the floor, walks quite well. It survives. 



The air of the oxygen bag contained at the beginning of the ex- 

 periment 86.4% of oxygen; at the end, it contained only 68.1% with 

 10.4% of carbonic acid. The oxygen tension then must have risen 

 to about 460, or 23 atmospheres. 



The liquid furnished by blood x discolors per 5 cc. between 10 

 and 15 drops of copper reagent; that of blood y discolors between 

 15 and 20. 



As to the consumption of oxygen, it was in experiment a 3.95 

 liters, and in experiment b it fell to 2.15 liters. The production of 

 carbonic acid also dropped from 2.41 liters to 1.99 liters. 



Experiment CCXCV. February 24. Female dog weighing 17 kilos. 



2:55; respiration by natural channels, calm; vaginal temperature 

 40°. I draw 33 cc. of carotid blood A 



3:12; I place a tube in the trachea; rapid respirations; then 1 

 take 500 gm. of arterial blood. 



3:47; took 25 cc. of blood (temperature 39°) B 



From 4:10 to 4:40, placed in the apparatus with a bag contain- 

 ing air with 93% oxygen. Pressure rises to 6 and % atmospheres. 



Decompressed suddenly, found dead, limp, temperature 37°. 



The oxygen tension had risen to about 580, that is, 29 atmos- 

 pheres of air. 



Blood A (natural respiration) O z 17.0; CO> 38.5 



Blood B (tracheal respiration, copious bleeding) O, 16.5; C0 2 14.4 



Experiment CCXCV I. February 25. Dog weighing 15 kilos. 



While he is breathing by the natural channels, I draw 33 cc. of 

 carotid blood A 



Rectal temperature is 40°. 



I then place a tube in the trachea, and extract in one hour 400 cc. 

 of arterial blood. He does not make any extraordinary or rapid 

 respirations, but his temperature drops to 37.5°; I take the last 33 cc. 

 of blood for analysis B 



From 3:45 to 4:40, raised to the pressure of 6V2 atmospheres, 

 with a bag containing air with 90% of oxygen. 



Taken out in strong convulsions, excitable by the introduction 

 of the thermometer into the rectum. Temperature 36°. 



The convulsions continue, and the animal dies during the night. 



The maximum oxygen tension was about 520, corresponding to 

 26 atmospheres of air. 



