Compressed Air; O, Poisoning 727 



reduction of the copper reagent. Nothing by sulfate of lime or 

 nitric acid. 



The animal is placed in a cage fitted to collect the urine. 



This urine, the next day, reduces copper reagent, giving an 

 abundant yellow precipitate. 

 Blood A (air, normal pressure) . . . . O, 15.8; CO, 43.0 



Blood B (oxygen; 4 atmospheres) O, 23.9; CO, 59.0 



Blood C (oxygen; 6V2 atmospheres) O, 28.7; CO, 69.4 



Blood D (air; returned to normal pressure, convulsions) 2 12.4; CO,9.9 



The bag contained at the beginning air with 88.6% of oxygen. 



At the moment when blood B was drawn, the oxygen tension was 

 about equivalent to 320, representing 16 atmospheres. For blood C, 

 the figures would be 480 and 24 atmospheres. 



Experiment CCLXXXVII. January 23. Temperature 16°. Large 

 dog. 



Rectal temperature 39°. Tube placed in the trachea at 3:15. Its 

 respiratory rhythm does not change noticeably; it was very rapid. 



At 3:53, its temperature dropped to 38.5°. 33 cc. of moderately 

 red blood drawn from the carotid A 



At 4:02, placed in the apparatus with the bag containing super- 

 oxygenated air. 



At 4: 15, pressure is 2 and % atmospheres. 



I drew 45 cc. of very red blood, containing no free gases, with 

 a manifest tendency to coagulation. An accident prevents me from 

 analyzing it for its gaseous content. 



At 4:38, pressure is 7% atmospheres. 



I again draw 45 cc. of very red blood, coagulating rapidly, in 

 which no free gases appeared B 



At 4:40, decompression in 2 minutes. 



Taken out in strong convulsions. Rectal temperature 37°. 



The convulsions, at first rather moderate, with intervals of 

 flaccidity, continue to increase in strength. In the intervals of tonic 

 convulsions, the animal moves its feet as if it were walking. The 

 tonic convulsions are so strong that the animal can be lifted like a 

 piece of wood, by one foot. Its feet are stiff, its body in right 

 pleurosthotonos, with opisthotonos of the neck, its eyes open, pro- 

 truding; the pupils dilated; it is vomiting. 



At 5 o'clock it dies. The heart continues to beat for some 

 minutes. 



At 5:10, drew 33 cc. of very dark blood with a catheter from the 

 left heart, which is no longer beating C 



There is no urine in the bladder; very severe pulmonary con- 

 gestion. 



Blood A (air, normal pressure) O, 17.2; CO, 22.3 



Blood B (oxygen, 7Va atmospheres) 2 30.1; CO, 72.3 



Blood C (after death) O, 1.4; CO, 29.0 



The air of the rubber bag, analyzed after the animal had been 

 taken from the apparatus, contained O, 74%; CO, 10%. 



At the moment when blood B was drawn, the oxygen tension 

 was about 540, equivalent to 27 atmospheres. 



