722 Experiments 



144, respiratory rate 24; blood pressure in the carotid varies between 

 15 and 17 cm. of mercury. 



At 3:38, drew 38 cc. of blood .... A 



Placed in the apparatus at 4: 10, with a bag full of a mixture with 

 89.5 per cent of oxygen. 



At 4:30, pressure is 5 atmospheres, maintained there. 



At 4:38, drew 43 cc. of very red blood; no gas escapes . . . . B 



At 4:40, decompression in 1% minutes. 



The animal is immediately withdrawn, the bag is removed, and 

 it is noted that it has already vomited in the apparatus. It vomits 

 again. It shows attacks of stiffening without clonic jerks. The temper- 

 ature is 36.5°: the arterial pressure from 11 to 12 cm.; pulse is 140, 

 respiratory rate 24. 



These attacks of convulsive stiffening last about 20 minutes. 



At 6 o'clock, the temperature is 35°, the arterial pressure 12 cm., 

 the pulse 140. The dog begins to be able to stand on its feet. 



At 6:30, the animal, whose cannula has been removed, remains 

 lying down with a sort of muscular trembling, resembling that of 

 phenol poisoning. Its eyes are sensitive, and the pupils contract and 

 dilate as if by tremors which are related to the quivering of the 

 limbs. There are occasional stiffenings of the front feet, but they can 

 easily be bent. 



The next day, in good health. 



The analyses gave the following results: 



A: Air, normal pressure; 100 cc. of blood contain: O, 17.0; CO : 

 39.0. 



B: 5 atmospheres of superoxygenated air: 100 cc. of blood con- 

 tain: CX 24.8; CO, 75.0. 



The gas in the bag after the experiment contains 76.2 of oxygen 

 and 8.1 of carbonic acid. The oxygen tension in B was then about 

 77 x 5 = 385. 



Experiment CCLXXX. November 25. Dog of average size. 



Tube in the trachea; left carotid exposed. 



Rectal temperature 38. IV 



3:12; drew 33 cc. of blood; the animal breathes quietly .... A 



Placed in the apparatus at 3:55, with oxygen bag; between the 

 bag and the tube in the trachea a flask is placed, at the bottom of 

 which are bits of potash; by this means I intend to diminish the 

 proportion of carbonic acid stored in the bag. 



4:25; pressure 7 atmospheres; at 4:28, with great difficulty drew 

 23 cc. of blood . . . . B 



4:38, pressure 7 x k atmospheres; sudden decompression. 



Withdrawn at 4:45, the animal's eyes are sensitive; its tempera- 

 ture is 36°; there are stiffenings of the hind legs and the neck; the 

 respiration seems suspended, the heart beats very feebly. 



After 10 mmutes the stiffenings increase, but the respiration re- 

 turns, and the heart beats more quickly and strongly. Soon after, 

 the animal again becomes limp, as it was when it was taken from the 

 apparatus; its respiration is weak; it dies at 5:50, without moving. 



At 5:20, its temperature was 34.5°; at 5:50, it had fallen to 33.5°. 



