Action of Carbonic Acid 



907 



<a 



<~ 



<N 





| b | c r | d I " e- • I f | |g|h 

 Oxygen of the I I 1 I III.' 



bag 182 |66.2 | 51.7 | I 42.5 | 39.0 | 35.0 | | 32.9 | 31.8 



CO, | |15.5 |29.7 | 1 37.3|40.3 | 42.1 1 | 45.2 | 45.7 



Oxygen of the | A B | | C I | D | | E | 



blood | 21.4 | 20.7 | | 21.0 I 1 23.2 | 18.7 



CO, of the | | || 



blood | 42.7 | 66.8 | | 88.7 I 



Rectal 



temperature |37.6° |35.8° 



Respiration | 21 | 43 



Pulse |- | 100 



Arterial 



pressure | 1 13-16 



I 

 -| 95.4 



j I I 



32.2° |31.2°| 30.8° | 29.5' 

 38 | 36 | 28 | 20 

 88 | 72 | 60 | 48 

 I 



14-161 



11-151 



97.5 | 



I I 



|28.5°| | 28° 



116 | I 8 



| 32 | | 28 



I I 



I I 8-10 



9.7 



114.2 



27° 

 

 D 



Experiment DCXVI. March 28. Dog weighing 11.5 kilos. 



2:58. I cause the dog to breathe through a muzzle in a bag in 

 which there has been left the air remaining from the dog of the pre- 

 ceding experiment. This air still contains 40% of carbonic acid. 



The dog then has a respiratory rate of 20; pulse 132; I have just 

 taken 25 cc. of blood from its carotid, before adjusting the bag .... A 



3 o'clock. Respiration 33; pulse 108; then suddenly the respira- 

 tion is speeded up remarkably, and rises to 168. 



3:03. Appears insensible; the skin of its leg is cut and its toes 

 are squeezed without any sign of sensibility. 



3:05. The pressure in the carotid varies between. 19 and 23 cm.; 

 I take 25 cc. of carotid blood B 



3:06. Respiration 24, very deep; the diaphragm not acting ,the 

 hollow of the stomach is flattened at each inspiration; pulse 180. 



3:12. Legs absolutely lacking sensitivity; the eye is sensitive; the 

 pupils contract in the light; but squeezing the toes causes no change 

 either in the state of the pupils or the arterial pressure. 



3:17. Respiration 22; pulse 126; arterial pressure from 15 to 20 

 cm.; temperature 39°. 



3:25. Respiration 24; pulse 104; temperature 39°; eye almost lack- 

 ing sensitivity. 



3:26. I remove the bag and allow the animal to breathe the free 



3:28. Respiration 44; deep; pulse 165. 



3:30. Sensitivity in the legs restored. 



Put down on the floor, cannot stand up, and shows signs of rigor. 



3:50. Begins to stand up, tries to walk, but shows a peculiar 

 type of movement, turning towards the left, with its hind part on 

 the floor. 



The head is turned, the left ear lowered, the left pupil dilated; 

 nystagmus of both eyes. 



These phenomena last about ten minutes, gradually lessening; 

 then the dog recovers completely. 



