908 Experiments 



Blood A (at the beginning) contained 19.1 of oxygen and 44.8 of CO,. 

 Blood B (insensibility) . . . contained 18.0 of oxygen and 81.2 of CO,. 



The, air of the bag, after the experiment, contained per 100: 

 CO, 43.6; 2 23.1. 



Experiment DCXVII. December 22. Bitch weighing 12.5 kilos. 



At 4:50, the animal is forced to breathe through a muzzle into 

 a bag containing a mixture of CO, 20%, oxygen 60%, nitrogen 20%. 



Before the experiment, the animal had a respiratory rate of 20, 

 pulse 80; the arterial pressure oscillated from 16 to 18 cm.; its tem- 

 perature was 38.5". I took 20 cc. of blood from its carotid A 



At the beginning of respiration in the bag, the animal took a 

 few very deep breaths, but soon became calm. 



5 o'clock. Quite sensitive everywhere; 44 deep respirations; the 

 pressure is 18 to 20 cm. 



5:30. Sensitivity when the paws are pinched is somewhat 

 blunted; respirations 36; pulse 64; pressure from 14 to 17 cm. 



5:40. I take 20 cc. of arterial blood B 



5:48. Sensitivity much dulled, even when the sciatic nerve is 

 stimulated; eye sensitive. 



6 o'clock. Respirations 28; pulse 80; temperature 36°. 

 The insensibility is making progress. 



6:30. Respirations 36; pulse 100; temperature 34.5°. 



Completely insensible to the piniching of the paws and the ears 

 and the electrical stimulation of the sciatic nerve. The eye is per- 

 haps a little sensitive yet. 



The arterial pressure oscillates between 11 and 17 cm.; I draw 

 air from the bag and 25 cc. of arterial blood C 



6:37. I unfasten the animal, remove the muzzle, and place the 

 animal on the floor. It is almost immediately seized by a great at- 

 tack of tonic, then of clonic convulsions, much like those of phenol. 



These convulsions diminish little by little. 25 minutes later, the 

 animal begins to stand up, but it is weak and tottering. 



7:20. Temperature 35°. The animal is stronger and more sensi- 

 tive. 



The next day it is quite well. 

 Blood A (outside air) contained. ....... O a 22.5; CO, 39.5 



Blood B (beginning of insensibility) 2 22.5; CO, 68.2 



Blood C (complete insensibility; air CO, 34.4; 2 43.8) O, 21.6; CO* 77.0 



Experiment DCXVIII. December 26. Dog; rubber muzzle. 



Respirations 20; pulse 88; arterial pressure from 18 to 19 cm.; 

 temperature 39.5°. 



At 5:07, caused to breathe into a bag containing a mixture of 

 52.8% of CO,; 36.7% of oxygen; and 11.5% of nitrogen. 



Almost immediately is seized by struggling with convulsive trem- 

 bling, which soon ceases. 



Anesthesia is complete 2 to 3 minutes afterwards; I then take 

 25 cc. of arterial blood .... A 



5:15. Removed the bag; immediately the respirations become 

 deeper and more frequent. 



5:18. Sensitivity has reappeared; I take 25 cc. of blood . . . . B 



