900 Experiments 



Tube in the trachea; carotid artery exposed. 



2:40. Caused to breathe into a bag containing about 30 liters of air; 

 at the end of 3 minutes, I draw 50 cc. of blood .... A 



Allowed to breathe free air. 



2:50. Again adjusted to the rubber bag, which contains 35 liters 

 of a mixture with about 90% oxygen. At 3 o'clock, drew 50 cc. of 

 blood evidently redder . . . . B 



4:05. Respiration becomes deeper; took air from the bag, which 

 contains 21.4% of CO.; drew 50 cc. of very red blood . . . . C 



4:35. Rectal temperature 35°. 



5:25. Rectal temperature 33°; at 5:30, took 50 cc. of blood . . . . D 



5:45. Took from the right heart, through the right jugular, 30 cc. 

 of very red blood . . . . E 



5:50. Drew air from the bag, which contains CO, 37..3; 2 48.8. 



A little air probably entered the heart, for the dog is seized by 

 trembling, convulsions, rigor; it is unfastened. 



6:15. Rectal temperature 34°. 



At 9 o'clock in the evening, is quite recovered; survives. 



A (air) contains per 100 cc. of blood 2 21.0; CO= 43.5 



B (oxygen) contains per 100 cc. of blood O^ 22.4; C0 2 43.9 



C (0 2 for 1 hr. 15 min.: C0 2 21.4) contains per 100 cc. of blood 

 Os 22.0; CO= 89.0 



D (0 2 for 2 hrs. 35 min.: CO. 35) contains per 100 cc. of blood 

 O. 19.9; CO= 87.2 



E (venous blood, CO, 37.3; 2 48.8) contains per 100 cc. of blood 

 2 16.5; CO= 82.3. 



Experiment DCVII. March 1. Large dog; muzzle. 



While it is breathing in the open air with extraordinary rapidity, 

 I draw 70 cc. of blood from the femoral artery .... A 



And from the vein, 40 cc A' 



3:45. Caused to breathe into a bag full of oxygen. 



3:50. Venous blood from the femoral. 40 cc B' 



3:55. Gas from the bag . . . . x 



3:58. Arterial blood, 40 cc B 



5:25. 30 or 40 calm respirations per minute; rectal temperature 37°; 

 took 40 cc. of arterial blood . . . . C 



The air of the bag contains CO, 32.8; 2 53.3 . . . . y 



At 6 o'clock, the animal is very sick; we inject carbonic acid care- 

 fully into the bag through a small orifice, taking pains by agitation 

 of the bag to obtain a mixture as perfect as possible. 



About 7 o'clock, it becomes evident that the animal is about to 

 die; we stop injecting the acid; rectal temperature 36°. The animal 

 breathes several times more. During the last respirations, I draw with 

 difficulty 47 cc. of very dark blood from the right heart . . . . D' 



Drew next, with just as much difficulty, from the left carotid 40 

 cc. of very red blood . . . . D 



Immediately after, took gas from the bag . . . . z 



I immediately place a tube in the trachea and collect under water 

 the air from the lungs, opening the thorax. It contains per 100: CO- 

 60.8; O, 18.8. 



