Action of Carbonic Acid 901 



Summary of the Experiment 

 A (free air; respirations very rapid; arterial blood) 

 A' (free air; respiration very rapid; venous blood) 

 B (air x: O 81.8; CO, 3.8; arterial blood) 

 B' (air x: 2 81.8; CO, 3.8; venous blood) 

 C (air y: 2 53.3; CO* 32.8; arterial blood) 

 D (air z: 2 37.6; CO, 51.5; arterial blood) 

 D' (air z: O* 37.6; CO, 51.5; venous blood) 



Experiment DCVIII. March 4. Dog weighing 3.950 kilos. 



Placed under a glass bell of 31 liters; brought the pressure to 17 

 cm.; is very uneasy, sits up anxiously: oxygen admitted. I then take 

 the pressure to 8 cm.: same symptoms, and oxygen admitted up to 

 normal pressure. 



The cock is closed at 2:45; the air contains 81% of oxygen. 



4:05. Animal uneasy, breathing with difficulty, sitting up in the 

 bell, air sample taken .... a 



5:30. The animal has just fallen on its side; air sample taken . . . b 



6:10. Lying down, does not heed raps on the bell, seems insensible; 

 16 enormous respirations, very painful; took air sample . . . . c 



9:30. Found dead; there has been absorption considerable enough 

 for the pressure to have diminished from 4 to 5 cm. in the bell; air 

 sample taken . . . . d 



So, in summary: 



Uneasy, with air a: O, 64.9; CO, 15.7. 



Falls, with air b: O, 60.5; CO, 20.2. 



Insensible, with air c: O, 53.8; CO, 27.0. 



Dead, with air d: O, 46.3; C0 2 34.1. 



Taking into account the diminution of pressure in the bell, we 

 easily calculate that there was about 1300 cc. of oxygen absorbed 

 without reappearing in the gaseous state as carbonic acid. 



Experiment DCIX. March 8. Medium-sized dog; cannula in the 

 trachea; femoral artery exposed. 



3:30. Caused to breathe in the bag containing air; respiration calm; 

 drew 50 cc. of blood from the femoral artery .... A 



3:53. Caused to breathe in the bag containing about 90% oxygen. 

 Shows almost complete apnea: merely a few slight respiratory move- 

 ments. At 4: 10, drew 50 cc. of very red blood . . . . B 



5:20. Forced respirations, very difficult; took air sample from the 

 bag; it contains CO, 9; Os 80.8. Drew 40 cc. of red blood . . . . C 



6:15. Rectal temperature 33°; respirations very uneasy; eye sensi- 

 tive. 



The air of the bag contains CO. 18; 2 70; drew 40 cc. of red blood 

 . . . . D 



Blood A (air) contains per 100 cc. of blood: O, 18.9; CO, 36.5 



Blood B (oxygen) contains per 100 cc. of blood: O, 23.0; CO, 42.8 



Blood C (O* 80.8; CO, 9) contains per 100 cc. of blood: 2 24.7; 

 C0 2 60.8 



Blood D (O, 70; CO, 18) contains per 100 cc. of blood: <)■-■ 17.6; 

 CO ; 71.6 



