662 Experiments 



At 4:40, pressure normal; respiratory rate has fallen to 24 and 

 pulse to 160. The arterial pressure cannot be ascertained exactly 

 because of clots. 



Experiment CCXIX. May 27. Dog, fastened in the big apparatus, 

 femoral artery exposed and cardiometer inserted. 



5:40. Normal pressure; respiratory rate 30; pulse 134; arterial 

 pressure 16 to 18 cm. 



5:55. Pressure 36 cm.; respiratory rate 60; the animal has been 

 struggling occasionally. 



6:05. Pressure 26 cm.; respiratory rate 70, uneven. Connection 

 made between artery and manometer; mercury rises and oscillates 

 between 16 and 18 cm. Pulse rate 160 to 180 per minute. 



Return to normal pressure in five minutes; respiratory rate 20. 

 The animal returns to normal state rapidly. 



Experiment CCXX. April 22. Cat brought rapidly to 26 cm. of 

 pressure under a current of air at 2:30. Cannot stand up, lies down 

 mewing. 



3:20. Respiratory rate 33. 



3:30. Brought back to 36 cm. because it seemed too sick. 



5:30. Still lying curled up. 



Taken out at 6 o'clock; did not urinate. 



Kept under bell, but at normal pressure, under continued current 

 of air. 



April 23. 10 o'clock in the morning, taken out. Has urinated; its 

 urine contains no sugar. 



Recovers entirely. 



Experiment CCXXI. May 14. Cat weighing 3.500 k. Hypodermic 

 of 10 centigrams of morphine hydrochloride. It is placed under a large 

 glass bell with a volume of 31 liters; its femoral artery is exposed, and 

 a copper wire passed around it records the pulse. The animal remains 

 quiet all through the experiment. 



At 4:30, at normal pressure, respiratory rate 25; pulse 105. 



Lowering of the pressure is then begun, leaving a current of air, 

 weak but sufficient to maintain the chemical purity of the air of the 

 bell. 



At 4:50, pressure 56 cm.; respiratory rate 40, pulse 120. 



At 5:10, pressure 46 cm.; respiratory rate 40, pulse 120. 



At 5:20, pressure 36 cm.; respiratory rate 48, pulse 132. 



At 5:30, pressure 26 cm.; the animal is much affected, weak, with 

 frequent convulsive starts; drools; respiratory rate 56, pulse 140. 



Pressure is lowered slowly to 20 cm.; the animal pants, shows 

 general convulsive movements, and dies at 5:45. 



The lungs are collapsed, without crepitation; superficial emphy- 

 sema; no pulmonary apoplexy. 



Dark blood in the left heart. 



Experiment CCXXII. February 28. Temperature 13°. 



Three rabbits of the same litter are placed at 2 o'clock under large 

 bells, on the apparatus in Figure 1. A current of air is maintained 

 under different pressures. 



