I052 



HANDBOOK (JF PHVSIOLOCl' 



NEUROPHYSIOLOGY II 



21" 2J'' 



A. Jonephin" 



A. Nucleus 

 paravenfric. 



22" 23'^ 

 A. Nucleus 

 supraopt 



Kern- 

 umgebung 



I I I 1 1 I ' M fi 



1 t t 



FIG. 21 . Lejt. Arterial pressure record of a decapitated cat following injection of epinephrine, pos- 

 terior lobe extract ('Tonephin"), extracts of the dog paraventricular and supraoptic nuclei, and an 

 extract of nervous tissue not including these nuclei ('Kernumgebung'). Right. Record of the contrac- 

 tion of the isolated virgin guinea pig uterus. Extracts of nervous tissue not including supraoptic or 

 paraventricular nuclei were added to the Tyrode solution at A and B. At C, an extract of the dog 

 supraoptic nucleus corresponding to 0.196 mg of dry tissue was added. [From Hild & Zetler (168).] 



T.\BLE I . .Mean A Inoliite Content of Posterior Lobe Hormones m Several Segments 

 of the Supraopticohypophyseal Tract of 10 Dogs 



Relative content of posterior lobe hormones in several segments of the supraopticohypophyseal tract following water de- 

 privation and rehydration; values arc expressed as per cent of the content in normal dogs do animals were present in each 

 group). 



A, antidiuretic hormone; V, vasopressin; O, oxytocin. 



* .Supraopticohypophyseal tract transected after the 14 davs of water deprivation. Froin Hild & Zetler (172). 



mones' (Bargmann) siiould be at least temporarily 

 discouraged, particularly since it has not been fully 

 established that the posterior lobe is simply a depot 

 for hormone and since the role of the pituicytcs in the 

 release of hormone is not clarified. 



The interpretation of the stainable neurosecretory 

 material as a carrier substance has received consider- 

 able support. Several considerations, however, are 

 difficult to harmonize with this hypothesis; a) the 

 almost identical content of sulfhvdryl groups in 



