Researches on the ferments of the brain 



by 

 Dr» Aurei D. Craifaleanu 



Meniber of the Society 



(Tornata del 19 agosto 1917) 



I. Introduction. 



II. Methods. 



III. Description of the Experiments. 



IV. Dlscussion of the resiilts. 



Proteolytic ferment?. 



Ferments splitting up the Phosphatides. 



Nuclease. 



V. Conclusions. 



I. — Introdtiction. 



The first researches on the proteolytic ferments of the 

 brain were made by Rosell ^) who found therein a ferment 

 capable to solubihse the fresh fibrin. Later Kutscher and Loh- 

 MANN "), who studied one oxesbrain, seem to have doubted the 

 existence of a proteolytic ferment therein. More precise resuits 

 have been obtained by Levene and Stookey ■') who found pro- 

 teolytic ferments in the brain of dogs. Simon ^) also found a 

 proteolytic ferment in the brain of calves and has shown the 

 existence therein of a ferment capable to break down the pho- 

 sphatides. Halliburton ■') and Levene ^) bave shown that among 

 the proteids of the brain is also found a nucleo-proteid. 



*) RoSELL, M. Inaug. Dissert. Strassburg, 1901. 



"-) Kutscher and Lohmann, Zeit. Physiolog. Chemie. Voi. 37 p. 317 (1903). 



■') Levene and Stookey, The Journal of Medicai Research, Boston, 1903 

 p. 212. 



') Simon, F. Zeit. Physiolog. Chemie. Voi. 72 p. 463 (1911). 



•"') Halliburton, Ergebnisse der Physiologie. Voi. 4 p. 30 (1905). 

 Journ. of Physiology. Voi. 15 p. 90 (1894). 



'■) Levene, P. A. Arch. of Neurol. and Psychopathol. 2 (1899). 



