/l/ Since fresh nerve tissue contains approximately T^% water, 

 values can be converted to a per mg dry weight basis by multi- 

 plying by k. /2/ Adult dog cerebral cortex slices, average 2.3 

 in Ca-free Ringer-phosphate; l.k in complete Ringer-bicarbonate; 

 and it.2l^ in a Ca-free phosphate saline medium supplemented with 

 pyruvate, fumarate, and glutamate. 



/!/ At one week the highest rate of glycolysis Is found In the medulla, while in the adult 

 It occurs In the caudate nucleus and cerebral cortex. In general, a slight recession from 

 the maximum glycolysis la observed In the adult. /2/ It has been verified that the dis- 

 placement of COg in measurements on the adult cat cerebral cortex Is due to the production 

 of lactic acid. It Is assumed that other parts of the cat brain also produce exclusively 

 lactic add under these conditions. 



228 



