/l/ Defined differently by every investigator. Both qualitative (dietary essentials) and quantitative (calories) deficien- 

 cies are present in the majority of studies. /2/ Deficiency probably acts via diminished secretion of pituitary gonadotro- 

 pins and the resultant hyixjfunctlon of the gonads. The capacity of the gonads and the accessory reproductive organs to re- 

 spond to hormonal stimuli Is apparently unimpaired, /3/ Effects of a deficiency in this nutrient are observed even when the 

 total caloric intake is maintained unchanged. /k/ Pregnancy can be maintained by estrone and progesterone. /^/ Linoleic, 

 llnolenlc, arachldonic acids. /6/ A generic term Including cyanocobalamln (vitamin B-j^p^ ^^"^ ^^^ hydrogenatlon product 

 (kzuvn variously as Bj^ga °'" ^2b^ which has approximately the same biological activity, ff/ Effect attributed to failure of 

 fetal mesodermal derivatives especially those concerned with hematopolesis, and to abnonDalities of the vascular system. /8/ 

 Folic acid is not a chemical entity, but a generic term for pteroylglutamic acid (folacln), vitamin M, vitamin B^,, factor U, 

 L. easel factor, Norlte eluate factor, /9/ Includes pyridoxlne, pyrldoxal, pyrldoxamine. /lO/ Thyroid insufficiency? /ll/ 

 Arginlne major structural component of nucleoproteins of sperm head. /12/ Also true for leucine, /13/ Also true for methio- 

 nine and threonine. 



164 



