115. EXCRETION Of VITAMINS AND HORMONES: MAN 



Because of the high degree of variability in rate of s«eat formation, ranging from zero under 

 some conditions, up to as high as 12 liters per day in extremely hot climates, it has not been 

 practicable to present data on excretion via sweat in terms of "per kg body weight per day". 



Constituent 



Excreted in Urine 



tjg/kg body -..-t/da 



Value 



Range-" 



m 



Excreted in Feces 



Hg/kg body irt/da 



Value 



imi 



R angel 



HI 



Excreted in Sweat 



Ug/lOO ml 



Value 



TfT 



Rcingel 



m 



im 



Vitamins 



li Vitamins A, D, K 

 2 Ascorbic acid 



5 Biotin 

 U] Carotenes 



Choline 



6 Cobalamin-' 



7 Vitamin E^ 



8 Folic acid group' 



9 Inositol 

 10| Nicotinic acid 



111 N-Methyl nicotinamide 

 12 Pantothenic acid 

 15 Para-aminobenzoic acid 

 Ik Pyridoxine 



15 Pyridoxal 



16 Pyridoxamine 



17 U-Pyridoxic acid 



18 Riboflavine 



19 Thiamine 

 20| Trigonelline 



380 

 O.lt 



90 



0-trace 

 130-790 

 0.33-0.75 



80-130 



o.oooi^ 0.00023-0.00079 



0.2 

 170 



130 

 2.11 

 3.0 



1.6 

 51 

 11^.3 



2.6 



0.03-0.5 



170-220 



11-105 



75-1+00 

 20-100 



2-5 



O.OO7-O.OO98 

 0.7-5.'+ 



0.5-2.1 



9-160 



0.2-22.5 



0.1*5-5.6 



50-500 



70 

 1.9 



508 

 k.3 



52 



31.'* 

 5.5 

 5A 



li*.7 



7.8 



60-70 

 0.65-6. 61* 

 20-600'* 



226-591 

 1.8-7.7 



12-12I* 



5.85-65.1* 

 1.01-8.2 

 2.1*-10.1* 



8.0-25 

 0.67-18 



tracer 



0.6 



21 



5.8 

 0.21* 

 0.081* 

 5.2 



0.015 



0-2002 



2.7-15.5 



0.55-0.88 



15-56 



7-22 



2.2-l*.l* 

 0.08-1.7 

 0.08-0.18 



0.1*-8.25 



0-0.5 

 0-0.6 



Hormones 



21 Androgens 



22 Estrogens 

 25 Formaldehydogenlc steroids 



21*1 LY-Ketostei-oids Id'l60;9100 

 25j Oxycorticosteroids I 



50-100 



0.1-0.5 



5-ll*0 



1.0-6.0 



/l/ Ranges are averages of ranges of values reported in the literature cited. They may be con- 

 sidered to be equivalent to estimate "d" of the 95/^ range (cf. Introduction). /2/ Ascorbic 

 and dehydroas corbie acid. /5/ Present but not quantitated. /!*/ Carotene and xanthophyll; 8-100 

 jig/kg body wt/da for xanthophyll alone. /5/ A generic term including cyanocobalamin (vitamin 

 B12) 3-'i<^ i^s hydrogenation product (known variously as 6^23 °r Bj^2b^ which has approximately the 

 same biological activity. /6/ A generic term for alpha-, beta-, delta-, and gamma-tocopherols . 

 /7/ Folic acid is not a chemical entity, but a generic term for pteroylglutamic acid (folacin), 

 vitamin M, vitamin B,,, factor U, L. casei factor, Norite eluate factor. 



212 



