4i6 



SUBJECT INDEX 



Barrier hypothesis of survival of skin 



homografts, 97-102, 112, 114 

 Barrier theory of immunological 



segregation of mother and foetus, 



119, 127, 131, 132, 133-135 

 Benzpyrine, tumours produced by, 



167, 169, 182 

 Blood groups, in rat, 24 



relation widi grafts, 22 

 Body fluids, serologically active 



substances in, 36 

 Bone marrow cells, acting as grafts, 3 

 Bone marrow transplantation, 164, 



177, 178, 180 



Calcium cliloride, effect on trans- 

 plantation antigens, 9, 10 

 Carbohydrate, in antigens, 88 

 Carcinogens, andhomograft response, 



402 

 Cartilage homografts, 105 

 Cells, tumour, see Tumour cells 

 Cheek pouch of hamster, epithehum, 

 grafting of, no 

 immunological response of, 112- 



113 



skin grafts of, preparation, 92-93 

 skin homografts in, 90-107 



anomalous behaviour of, 96-97 



barrier hypothesis of survival, 

 97-102, 112, 114 



destruction of, loi 



destruction by adoptive immuni- 

 zation, 97, 109 



effect of hyaluronidase, loi, 115, 

 116 



effect of cortisone on, 102-103 



fate of, 94-96 



importance of lymphatic drain- 

 age, 98, 103, 113, 114 



inlaying of, 98-99, 104, 112 



prolongation of, 99 



reasons for rejection, 97 



reasons for survival, 101-102 



Cheek pouch of hamster, 

 skin isografts, fate of, 93-94 

 special properties of, 112 



Chimeras, radiation, see Radiation 

 chimeras 



Chimerism, analysis of, 1 41-143 

 cytological test for, 338 

 in parabionts, 33°, 337-339 

 in survivors of runt disease, 252, 

 265, 268-269 



Chorionepithehoma, treatment of by 

 immunization, 133 



Clonal selection theory, 185-187, 

 200-205, 259 

 antibody formation in, 201 

 antigenic strength and, 206 

 hypothesis of, 207-208 

 intracellular basis of, 202, 206 

 loss mutation as basis, 202-204, 



207 

 role of antigenic strength, 207 

 role of lymphoid cells, 214 



Competitive replacement, 331 



Connective tissue, inactivation of 

 antigens by, 115 



Cornea, not immunologically 

 privileged tissue, 105 



Cortisone, effect on metastasis, 168, 

 169, 183-184 

 effect on pouch skin homografts, 



102-103 

 in runt disease, 352, 367-369 



Delayed hypersensitivity, 



bacterial, 277-278, 280 



and transfer factor, 272-274 



dual response in, 409-410 



homograft rejection, 275, 276, 278, 

 283 



in premature infants, 149 



transfer factor, 283 

 Delayed sensitivity, fungal, 272, 278 

 Density gradients, in extraction of 



H-2 antigens, 52-53 



